Ask HN: Who is hiring? (July 2026)

St. Jude Children's Research Hospital | Sr. Staff or Principal Software Engineer, Rust Genomics Infrastructure | Memphis, TN | ONSITE (2x/week onsite) or REMOTE | $125,840 - $238,160 | https://www.stjude.org/

St. Jude Children's Research Hospital is hiring Rust software engineers to rebuild the genomics ecosystem in Rust. We work at the intersection of computer science and genomics, and we're trying to build a better foundation upon which genomics can be done using Rust. The primary project we’re working on is a bioinformatics workflow execution engine for local, HPC, and Cloud called Sprocket (https://github.com/stjude-rust-labs/sprocket). You can also check out the other projects we have going on at https://github.com/stjude-rust-labs.

NOTE that prior experience in bioinformatics or biology is NOT required for any of the positions below. You must be interested in learning though! If you'd like to get a sense of what you'd be learning, check out the guide we wrote to teach software engineers about genomics here: https://learngenomics.dev.

* Sr. Staff or Principal Software Engineer: https://talent.stjude.org/careers/JobDetail/Senior-Staff-Pri...

With any questions, email me at clay.mcleod@stjude.org. Please do not email me your application directly—be sure to submit it through the job portal.

Prophet Town LLC | Various Software Engineering Roles | US – Remote and Hybrid | English fluency required | Full-time | $150K-$260K annual total comp (multiple)

We are a people-first, boutique tech agency creating on-demand teams and software solutions for long-standing clients. These clients trust us to practice engineering excellence as though we were members of their own staff. Our leadership team is ex-Fortune 100 with software engineering backgrounds: we’re still coding. Notable recent projects include a gigantic ERP migration for Anduril Industries, and a skunkworks with Surge Labs helping to develop some of the frontier LLM models themselves (yes, seriously). This is a remote-first agency, but some projects involve onsite work.

I’m the founder and CEO, and I’m trying to do what I call “enlightened business”. I take responsibility for both staff and clients, and I look for people who approach their work with a similar sense of ownership. Applicants must meet a high bar - I personally review every hire. In return you’ll get:

  * Flexibility and a low-bureaucracy environment
  * Clients that won’t treat the vendor like “the B Team”
  * The chance to act as a code architect, not just implement tickets
  * Exposure to a wide variety of industries and modern challenges
  * Me as your personal champion and advocate

Feel free to submit, even if you already did in the past.

We’re currently especially seeking:

Back-end, Front-end, and Full-Stack Software Engineers, Tiers 3 and 4 (Typescript/Javascript, React, NextJS; Ruby on Rails; Python; DevOps, and third-party API integrations)

Tier 3 roles are typically 5-10 years experience with $150-$180K total comp.

Tier 4 roles are 11-20 years experience, $215-$260K total comp.

Higher tiers exist, and we always welcome exceptional applications.

Though not yet universal, many of our clients are now demanding senior/staff engineers with success using modern agentic approaches. Be ready to explain where current models work well and where they do not.

Please apply using this Google Form: https://forms.gle/Ec9WgTTakAV8HcAx9

Annex Risk | Full-stack + Backend Engineer | Bay Area, Austin | Full-time

The cost of homeowners insurance, especially in natural catastrophe prone areas, has skyrocketed in recent years. Annex is solving this problem with better digital infrastructure for executing the transaction. Our platform enables insurance agents to quote and bind policies within 90 seconds vs. the current multi-day phone/email/fax-based transaction that is the status quo.

We grew 4x in 2025 and anticipate similar growth in 2026. We've done the above after deploying We're in that exciting early stage, where someone can contribute foundational new pieces to core parts of our platform.

More details at:

Full-stack Engineer: https://wellfound.com/jobs/4130991-software-engineer-full-st...

Backend Engineer: https://wellfound.com/jobs/3060211-software-engineer-backend

You posted in the wrong thread, hopefully dang will swing by to remove this subthread.

Please post here: https://news.ycombinator.com/item?id=48747975