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Healthy but sedentary people show early decline in cellular energy production

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Re: Healthy but sedentary people show early decline in cellular energy production

#11

Post by sidewndr46 »

nine_k wrote: post #3

> mitochondria, which process energy within cells, showed a significantly decreased capacity to burn both sugar and fat in healthy individuals who get less than the recommended 150 minutes of exercise a week. 150 minutes a week is about than 22 minutes a day. Like 11 minutes twice a day. This looks like a really low effort to rid oneself of the risk of early decline.

I've seen studies like this before. They'll suggest that as little as 15 minutes of exercise significantly improves health in some group they studied. My initial assumption was they added 15 minutes of additional exercise. No, they studied people who did literally nothing. Then had them exercise 15 minutes a day.

As you might guess, their outcomes improved greatly.

Re: Healthy but sedentary people show early decline in cellular energy production

#12

Post by fhdkweig »

jr3592 wrote: post #8
wonderwonder wrote: post #7

Seems like a potential use for peptides like Mots-C or SLU-PP-332

It would be cool if one could safely adapt to modern life (lots of sitting, required focus over long sessions) without having to spend time exercising if they don't want to (to be clear, some people want to). Imagine if you could just take something to get all the benefits of exercise, without having to actually spend the time. That'd be pretty great for everyone if it truly was safe and without downsides (skeptical)…

They make stationary bikes that fit under a desk. I've never used or seen one, but they exist. I considered getting one during 2020, but they seemed impossible to source.

https://duckduckgo.com/?q=desk+stationary+bike

Re: Healthy but sedentary people show early decline in cellular energy production

#13

Post by DeluluDon »

jr3592 wrote: post #8
wonderwonder wrote: post #7

Seems like a potential use for peptides like Mots-C or SLU-PP-332

It would be cool if one could safely adapt to modern life (lots of sitting, required focus over long sessions) without having to spend time exercising if they don't want to (to be clear, some people want to). Imagine if you could just take something to get all the benefits of exercise, without having to actually spend the time. That'd be pretty great for everyone if it truly was safe and without downsides (skeptical)…

[dead]

Re: Healthy but sedentary people show early decline in cellular energy production

#14

Post by SchemaLoad »

sidewndr46 wrote: post #11
nine_k wrote: post #3

> mitochondria, which process energy within cells, showed a significantly decreased capacity to burn both sugar and fat in healthy individuals who get less than the recommended 150 minutes of exercise a week. 150 minutes a week is about than 22 minutes a day. Like 11 minutes twice a day. This looks like a really low effort to rid oneself of the risk of early decline.

I've seen studies like this before. They'll suggest that as little as 15 minutes of exercise significantly improves health in some group they studied. My initial assumption was they added 15 minutes of additional exercise. No, they studied people who did literally nothing. Then had them exercise 15 minutes a day. As you might guess, their outcomes improved greatly.

This is sadly not a rare type of person. I'm worried my parents fit this description, they drive everywhere and work an office job. I'd guess on average they get 0 minutes of exercise a day.

I think people get this image in their head that someone who doesn't exercise ever is this comically fat unemployed person when in reality it's the average office worker who isn't fitness minded. A good chunk of HN users wouldn't be getting 15 minutes of exercise a day.

Re: Healthy but sedentary people show early decline in cellular energy production

#15

Post by free652 »

sidewndr46 wrote: post #11
nine_k wrote: post #3

> mitochondria, which process energy within cells, showed a significantly decreased capacity to burn both sugar and fat in healthy individuals who get less than the recommended 150 minutes of exercise a week. 150 minutes a week is about than 22 minutes a day. Like 11 minutes twice a day. This looks like a really low effort to rid oneself of the risk of early decline.

I've seen studies like this before. They'll suggest that as little as 15 minutes of exercise significantly improves health in some group they studied. My initial assumption was they added 15 minutes of additional exercise. No, they studied people who did literally nothing. Then had them exercise 15 minutes a day. As you might guess, their outcomes improved greatly.

15 mins of walking or exercise. I did 2 hours of walking 15k steps and it's barely moved my required cardio load to 10 and I need over 200 weekly.

Re: Healthy but sedentary people show early decline in cellular energy production

#16

Post by [deleted] »

nine_k wrote: post #3

> mitochondria, which process energy within cells, showed a significantly decreased capacity to burn both sugar and fat in healthy individuals who get less than the recommended 150 minutes of exercise a week. 150 minutes a week is about than 22 minutes a day. Like 11 minutes twice a day. This looks like a really low effort to rid oneself of the risk of early decline.

[deleted]

Re: Healthy but sedentary people show early decline in cellular energy production

#17

Post by wonderwonder »

fhdkweig wrote: post #12
jr3592 wrote: post #8

Earlier quoted context omitted.

It would be cool if one could safely adapt to modern life (lots of sitting, required focus over long sessions) without having to spend time exercising if they don't want to (to be clear, some people want to). Imagine if you could just take something to get all the benefits of exercise, without having to actually spend the time. That'd be pretty great for everyone if it truly was safe and without downsides (skeptical)…

They make stationary bikes that fit under a desk. I've never used or seen one, but they exist. I considered getting one during 2020, but they seemed impossible to source. https://duckduckgo.com/?q=desk+stationary+bike

they make walking pads as well for the desk; I've never used one but have seen some people who seem happy with them

Re: Healthy but sedentary people show early decline in cellular energy production

#18

Post by Fricken »

nine_k wrote: post #3

> mitochondria, which process energy within cells, showed a significantly decreased capacity to burn both sugar and fat in healthy individuals who get less than the recommended 150 minutes of exercise a week. 150 minutes a week is about than 22 minutes a day. Like 11 minutes twice a day. This looks like a really low effort to rid oneself of the risk of early decline.

A studied showed that elderly asians have better health outcomes that their western counterparts in part due to their practice of sitting on the floor. The added exertion of standing up from the floor rather than a chair makes a material difference in their health.

Re: Healthy but sedentary people show early decline in cellular energy production

#19

Post by adam_arthur »

jsw97 wrote: post #2

19 subjects, assigned sedentary or active based on habitual physical activity levels. Subjects were screened on basic health measures. The problem with this is that people are sedentary or active for a variety of health-related reasons that are not captured in any screen (esp. the crude one used in this study). As a predictive study, this is fine, sedentarism predicts a lot of bad things. But it doesn't, on its own,…

The principle of what you're stating is true, it could be correlational.

But there's an enormous volume of evidence that exercise, especially intense exercise, is better for health than any other intervention, including more sleep, quality of diet, pills+supplements (except those that treat an active illness/disease of course).

There's even compelling data showing that moderate drinkers who exercise live longer than non-drinkers who don't exercise. Even given that Alcohol is a powerful carcinogen.

The only thing proven more effective than exercise is weight loss really, if starting from high bodyfat levels.

(Anything above ~15% bodyfat in men seems to have negative implications for lifespan, and ~30% for women)

Re: Healthy but sedentary people show early decline in cellular energy production

#20

Post by Gigachad »

Fricken wrote: post #18
nine_k wrote: post #3

> mitochondria, which process energy within cells, showed a significantly decreased capacity to burn both sugar and fat in healthy individuals who get less than the recommended 150 minutes of exercise a week. 150 minutes a week is about than 22 minutes a day. Like 11 minutes twice a day. This looks like a really low effort to rid oneself of the risk of early decline.

A studied showed that elderly asians have better health outcomes that their western counterparts in part due to their practice of sitting on the floor. The added exertion of standing up from the floor rather than a chair makes a material difference in their health.

At least in China they also have a lot of public parks where they all gather for group exercise with all the other elderly people.
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