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Healthy but sedentary people show early decline in cellular energy production

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Re: Healthy but sedentary people show early decline in cellular energy production

#2
19 subjects, assigned sedentary or active based on habitual physical activity levels. Subjects were screened on basic health measures.

The problem with this is that people are sedentary or active for a variety of health-related reasons that are not captured in any screen (esp. the crude one used in this study). As a predictive study, this is fine, sedentarism predicts a lot of bad things. But it doesn't, on its own, suggest that becoming active is helpful. See also grip strength and mortality.

Re: Healthy but sedentary people show early decline in cellular energy production

#3
> mitochondria, which process energy within cells, showed a significantly decreased capacity to burn both sugar and fat in healthy individuals who get less than the recommended 150 minutes of exercise a week.

150 minutes a week is about than 22 minutes a day. Like 11 minutes twice a day. This looks like a really low effort to rid oneself of the risk of early decline.

Re: Healthy but sedentary people show early decline in cellular energy production

#8

Seems like a potential use for peptides like Mots-C or SLU-PP-332

It would be cool if one could safely adapt to modern life (lots of sitting, required focus over long sessions) without having to spend time exercising if they don't want to (to be clear, some people want to). Imagine if you could just take something to get all the benefits of exercise, without having to actually spend the time. That'd be pretty great for everyone if it truly was safe and without downsides (skeptical).

Re: Healthy but sedentary people show early decline in cellular energy production

#9
post #3

> mitochondria, which process energy within cells, showed a significantly decreased capacity to burn both sugar and fat in healthy individuals who get less than the recommended 150 minutes of exercise a week. 150 minutes a week is about than 22 minutes a day. Like 11 minutes twice a day. This looks like a really low effort to rid oneself of the risk of early decline.

A lot of people who use a car to get around will spend most days doing literally no actual exercise. For someone who lives in a more walkable area, 22 minutes of exercise is just living live normally without actively "exercising".

Re: Healthy but sedentary people show early decline in cellular energy production

#10
post #8

Seems like a potential use for peptides like Mots-C or SLU-PP-332

It would be cool if one could safely adapt to modern life (lots of sitting, required focus over long sessions) without having to spend time exercising if they don't want to (to be clear, some people want to). Imagine if you could just take something to get all the benefits of exercise, without having to actually spend the time. That'd be pretty great for everyone if it truly was safe and without downsides (skeptical)…

What if we could just lay in a pod 24/7 taking peptides and nutrient supplements while having an endless stream of instagram reals beamed in to our eyeballs on our Meta Raybans. That way we would never have to do pesky things like go outside or move.
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