Live data from Hacker News

Ending respiratory infections

blog.interceptfund.com

71–80 of 146 posts

Re: Ending respiratory infections

#71
post #3

My girlfriend died from human metapneumovirus at 30 years young. She had a weakened immune system from lymphangiomatosis, so something like metapneumovirus, which is a mild illness for most people, was a death sentence for her. I hope this fund is successful so nobody else ever has to go through what she did.

This is the kind of thing people miss when they say "it's just a cold". I really hope this work goes somewhere.

Re: Ending respiratory infections

#72
post #24

It's sad we're resorting to philanthropy to solve problems like this. $500M is chump change. NASA spent something like $300B in today's money on the Apollo program, and Artemis has exceeded $90B already. I'm much more keen on never getting sick than prepping for Mars.

It's strange how much we've normalized everyone being sick for weeks every year, even though the total cost is enormous

Re: Ending respiratory infections

#73
> So, to get closer to elimination, we also need a way to reduce the virions circulating in high density environments. During COVID the world experimented with various interventions like social distancing and personal protective equipment. But to reduce transmission durably for a large number of common respiratory viruses that are perennially circulating, we need solutions that are convenient and minimally disruptive.

We think the most promising category of products that accomplish these goals are those that remove pathogens from the air, particularly in high-density environments like offices, schools, and public transit. We’ll call these air cleaning technologies (ACTs) like air filtration and far-UVC antimicrobial light.

Sounds like a pretty big challenge to me... Ok, during Covid I read that airplane-style air conditioning with nozzles above each seat and used air pumped out at ground level was pretty good in making sure "your" air didn't get mixed up with your neighbor's (masks were still mandatory however on the few flights I took during that period). But how are you going to do the same in a packed subway train in, let's say, Tokyo or New York, at rush hour? That air conditioning unit would probably have to be as heavy as the train itself, and to the passengers it would feel like a hairdryer (on cold setting) blasting at them permanently from above...

Re: Ending respiratory infections

#74

> Healthy people spend roughly 15-25 days each year—about 5% of their lives—sick with respiratory infections like the common cold and influenza This seems completely unbelievable to me. Totally outside of my personal, professional, and family experience.

I guess it depends a lot on what they count as sick. I definitely don't spend 3 weeks a year in bed, but if you add up all the random sore throats, congestion, coughs that linger for a week and "not really sick but clearly fighting something" days, it may be less crazy than it sounds

Re: Ending respiratory infections

#75

> Healthy people spend roughly 15-25 days each year—about 5% of their lives—sick with respiratory infections like the common cold and influenza This seems completely unbelievable to me. Totally outside of my personal, professional, and family experience.

No kids eh? My oldest starting preschool was one of the worst times in my life. We were sick from august to december, then january to may. Dreadful. It got better. My youngest is 3 now and is ahead of where my oldest was due to having 2 older siblings importing illnesses for several years, and this year we finally were mostly not sick all school year. Which is to say, we were probably closer to the 15 days "materiall…

Kids don't just get sick, they seem to turn the whole house into a slow-motion relay race of viruses

Re: Ending respiratory infections

#76
post #24

It's sad we're resorting to philanthropy to solve problems like this. $500M is chump change. NASA spent something like $300B in today's money on the Apollo program, and Artemis has exceeded $90B already. I'm much more keen on never getting sick than prepping for Mars.

It’s 500m spend without guaranteed success.

remind me how successful the Iran war was

Re: Ending respiratory infections

#77

Earlier quoted context omitted.

It’s 500m spend without guaranteed success.

[flagged]

Other people getting assistance too don't take away anything from your friend at all. If you want to be angry, be angry about your government spending trillions for the military and billionaires, not about the weakest parts of society.

Re: Ending respiratory infections

#78
post #50

Earlier quoted context omitted.

Everything should be voluntary philantrhopy! It seems like the ideal state if people are willing to do the pro-social thing by their own volition. Is it better if your child does their homework because they freely choose to, or is it better that they do it because you will beat them with a belt?

I'm sure if we just cut taxes a little more, our modern-day robber barons will choose to use their money to fix things on their own instead of building doomsday bunkers and buying superyachts.

it will start to trickle down any moment now!

Re: Ending respiratory infections

#79
the premise is wildly disengenious in conflating the pureification of water supplys, and air. a simple set of facts is that humans now represent the largest mass and population of large animals ever to exist. this population inhabits many habitats , both natural and constructed. this population has huge numbers of indivuals who have compromised imune systems. and last, but worst is that humans now constitute a biological niche, and a primary law of biology is the "all niches will be filled"

Re: Ending respiratory infections

#80
post #68

Maybe they can send some of this money to the Wuhan Institive of Virology to research respiratory viruses in bats and some to Raph Baric at UNC for vaccine development. What could go wrong?

Hard to tell. They might have equally well found something helpful if it weren't for the incident.
Post reply on HN