41–50 of 308 posts
Has anyone done a RCT of D3+K2? K2 seems to be important in the absorption of D3. Another aspect that bothers me with these studies is that we’re simply supplementing the vitamin D, seemingly without measuring the change in blood levels. I took 2000IU (+K2) a day for many years in between testing my blood levels and still had <30ng/ml and had to go up to 5000IU/day. I’d like to see some further study.
https://pubmed.ncbi.nlm.nih.gov/33549285/
Look at the molecular structure
https://en.wikipedia.org/wiki/Vitamin_D
that's a freakin' steroid with one of the bonds in the rings deleted
Has anyone done a RCT of D3+K2? K2 seems to be important in the absorption of D3. Another aspect that bothers me with these studies is that we’re simply supplementing the vitamin D, seemingly without measuring the change in blood levels. I took 2000IU (+K2) a day for many years in between testing my blood levels and still had <30ng/ml and had to go up to 5000IU/day. I’d like to see some further study.
Those are both very important. I take a Vitamin D + K2 softgel with a meal that has some fat in it.
Has anyone done a RCT of D3+K2? K2 seems to be important in the absorption of D3. Another aspect that bothers me with these studies is that we’re simply supplementing the vitamin D, seemingly without measuring the change in blood levels. I took 2000IU (+K2) a day for many years in between testing my blood levels and still had <30ng/ml and had to go up to 5000IU/day. I’d like to see some further study.
Has anyone done a RCT of D3+K2? K2 seems to be important in the absorption of D3. Another aspect that bothers me with these studies is that we’re simply supplementing the vitamin D, seemingly without measuring the change in blood levels. I took 2000IU (+K2) a day for many years in between testing my blood levels and still had <30ng/ml and had to go up to 5000IU/day. I’d like to see some further study.
Your body needs vitamins in order to form complex aminos to operate. But your body only needs to make so many of them - especially if you are an adult, not pregnant, or not suffering from a disease of some sort. The very premise that loading up your body with "excess" vitamins beyond what you need is already pretty fraught. Building a house without enough lumber can lead to long term deficiency - but loading up a con…
Vitamin D deficiency entered the chat. It's a relatively common issue in many countries.
Your body needs vitamins in order to form complex aminos to operate. But your body only needs to make so many of them - especially if you are an adult, not pregnant, or not suffering from a disease of some sort. The very premise that loading up your body with "excess" vitamins beyond what you need is already pretty fraught. Building a house without enough lumber can lead to long term deficiency - but loading up a con…
https://en.wikipedia.org/wiki/Thiamine#Biological_functions
Vitamin D is not but rather it regulates calcium and phosphorous metabolism.
It's arguable whether Vitamin D is really a vitamin or a hormone, see https://pubmed.ncbi.nlm.nih.gov/33549285/ Look at the molecular structure https://en.wikipedia.org/wiki/Vitamin_D that's a freakin' steroid with one of the bonds in the rings deleted https://en.wikipedia.org/wiki/Secosteroid
The "Vitamin D" moniker has just stuck around since it was named in 1922.
I think a good hypothesis for the discrepancy regarding why people with "naturally" high levels of vitamin D fare better than those who do not has to do with how vitamin D is produced naturally.
If you take the vitamin orally it might help for rickets and a few other issues but if you take it naturally via sunlight you might actually be having other benefits that aren't properly measured today.
With the current state of fear surrounding sunlight I doubt people are getting enough to see benefits and all studies use oral supplements instead of time in sunshine.
The survey in the article that assessed vitamin D deficiency was a bit odd: > Because physical exams are performed in mobile vans in NHANES, data could not be collected in northern latitudes during the winter; instead data were collected in northern latitudes during summer and in southern latitudes in winter. To address this season-latitude aspect of the NHANES design, we stratified the sample into two seasonal subpo…