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The worthlessness of Vitamin D is mildly exaggerated

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Re: The worthlessness of Vitamin D is mildly exaggerated

#21

I suspect that blood vitamin D is mainly a marker for how much outdoor exercise people are getting, and that it is the exercise rather than the D which is causal.

My life changed after I got tested for vit D and started talking supplements. I was severely deficient. I am now sufficient and everything changed for me.

What exactly changed?

Re: The worthlessness of Vitamin D is mildly exaggerated

#22
post #5

Earlier quoted context omitted.

But then why do we see improvements in people that get vitamin D + K2 supplements and not exercise?

As the article mentions, we pretty much don't see improvements with supplementation.

From the article:

> the balance of evidence tips pretty clearly in the direction that people with low-ish levels would be wise to supplement

Re: The worthlessness of Vitamin D is mildly exaggerated

#23

I suspect that blood vitamin D is mainly a marker for how much outdoor exercise people are getting, and that it is the exercise rather than the D which is causal.

Maybe this is true if you’re only considering white people. Brown people can spend a lot of time outdoors and still be deficient, especially if their ancestry is from much a much sunnier region or lifestyle than the one they’re currently living in.

Re: The worthlessness of Vitamin D is mildly exaggerated

#24
post #7

This is a refreshingly balanced and honest analysis of Vitamin D studies. The strongest evidence for Vitamin D is in people who are severely deficient. Bumping up to a normal range can provide some improvements. The health influencers started noticing that the Vitamin D studies coming out weren't matching their original hype for Vitamin D, so many pivoted to trying to make claims that most people are severely deficie…

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Re: The worthlessness of Vitamin D is mildly exaggerated

#25
post #7

This is a refreshingly balanced and honest analysis of Vitamin D studies. The strongest evidence for Vitamin D is in people who are severely deficient. Bumping up to a normal range can provide some improvements. The health influencers started noticing that the Vitamin D studies coming out weren't matching their original hype for Vitamin D, so many pivoted to trying to make claims that most people are severely deficie…

On a slight tangent, if people are unaware, you can pay for and get just about any lab test without a prescription in the United States.

My PCP uses Quest Diagnostics and a vitamin d test is, I think, about $50. No fasting needed for it, nor prescription.

Re: The worthlessness of Vitamin D is mildly exaggerated

#26
Your body needs vitamins in order to form complex aminos to operate. But your body only needs to make so many of them - especially if you are an adult, not pregnant, or not suffering from a disease of some sort.

The very premise that loading up your body with "excess" vitamins beyond what you need is already pretty fraught. Building a house without enough lumber can lead to long term deficiency - but loading up a construction site with more materials than are needed shouldn't automatically be assumed to be good.

The reality is that the modern diet has already solved so many common nutrient deficiency diseases (pellagra and goiters were a shockingly common diseases 100 years ago) that maxing out on vitamin intake has become more of something like a speculative hobby than anything else.

Re: The worthlessness of Vitamin D is mildly exaggerated

#27
post #19

Has anyone done a RCT of D3+K2? K2 seems to be important in the absorption of D3. Another aspect that bothers me with these studies is that we’re simply supplementing the vitamin D, seemingly without measuring the change in blood levels. I took 2000IU (+K2) a day for many years in between testing my blood levels and still had <30ng/ml and had to go up to 5000IU/day. I’d like to see some further study.

> I took 2000IU (+K2) a day for many years in between testing my blood levels and still had Likewise, 23ng/ml while taking 2000iu/day of dry vitamin-d.

Switched to 5000iu +K2 in MCT oil, -- 8 months later I'm at 64ng/ml.

Re: The worthlessness of Vitamin D is mildly exaggerated

#28
post #5

Earlier quoted context omitted.

But then why do we see improvements in people that get vitamin D + K2 supplements and not exercise?

As the article mentions, we pretty much don't see improvements with supplementation.

I don’t think there’s anything definitive. 400IU/day from one study is nothing if you’re deficient. 2000IU from another study is better, but even then we don’t seem to know much about absorption from these studies. For example, did it actually raise serum levels by 10ng/ml after a year, and how did THAT correlate to positive or negative health outcomes? K2 also seems to play an important symbiotic relationship with D, and seems notably absent from these studies.

Re: The worthlessness of Vitamin D is mildly exaggerated

#29
This is great. I wonder if there's something like a patreon model where we could sponsor similar deep dives on other supplements?

For example, I've been supplementing with nicotinamide riboside for a few years now. I stop occasionally and when I do stiff and sore hands and knees return and I get more headaches.

I'd love to know if I'm deluding myself (placebo effect?) or there's good science that backs up my experience.

Re: The worthlessness of Vitamin D is mildly exaggerated

#30
> For a while there, many people thought vitamin D was magical

I never heard that in Germany. I only heard that if you use certain medications like cortisone that vitamin d could be problematic. Most doctors will give vitamin d supplements when prescribing cortisone, at least in Germany.

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