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HPV vaccine cuts risk of dying from cervical cancer before 30

theguardian.com

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Re: HPV vaccine cuts risk of dying from cervical cancer before 30

#3
post #2

From what risk level without them? How many people actually die of cervical cancer before age 30?? I mean, vaccinations and cancer prevention are both great, but this headline is ridiculous.

Your questions are sort-of answered in the article. 3300 die each year of cervical cancer in the uk. So at 0% it saves 3300 lives per year. However the vaccination is fairly new so they have to wait longer to see if it applies 20-years, 30-years, etc later. I assume it would though.

Re: HPV vaccine cuts risk of dying from cervical cancer before 30

#4
post #2

From what risk level without them? How many people actually die of cervical cancer before age 30?? I mean, vaccinations and cancer prevention are both great, but this headline is ridiculous.

Your questions are sort-of answered in the article. 3300 die each year of cervical cancer in the uk. So at 0% it saves 3300 lives per year. However the vaccination is fairly new so they have to wait longer to see if it applies 20-years, 30-years, etc later. I assume it would though.

Parent's question isn't answered in the article - no figure is given for how many deaths under 30 there are as a baseline.

From the article:

“We estimate that since its introduction [in 2008], HPV vaccination has prevented nearly 200 young women from dying from cervical cancer in England.”

This is an estimate of 200 total of any age total across 18 years. The article doesn't say 3300 die each year, 3300 are diagnosed each year.

Re: HPV vaccine cuts risk of dying from cervical cancer before 30

#5
post #2

From what risk level without them? How many people actually die of cervical cancer before age 30?? I mean, vaccinations and cancer prevention are both great, but this headline is ridiculous.

The estimated number of deaths from cervical cancer in the US in 2026 is 4,200. The death rate is 2.2 per 100,000 people down from 3.1 per 100,000 in 1992.

If we multiply 3.1e-5 by 50 years that's about a 0.15% chance of dying of this cancer. The HPV shots cost $500-1000 for the three shots, so the cost per life saved is about $650K. With the statistical value of a human life being about $12M this is quite cost effective.

I'm assuming the reduction in death continues to later in life after 30, but that's a reasonable assumption, IMO.

Re: HPV vaccine cuts risk of dying from cervical cancer before 30

#6
post #2

From what risk level without them? How many people actually die of cervical cancer before age 30?? I mean, vaccinations and cancer prevention are both great, but this headline is ridiculous.

> From what risk level without them?

“Approximately 0.6 percent of women will be diagnosed with cervical cancer at some point during their lifetime, based on 2021–2023 data” [1].

Given “reports of serious health issues after HPV vaccination were consistently rare—around 1.8 per 100,000 HPV vaccine doses, or 0.0018%” [2], a woman suffers a 300x higher hazard (assuming we measure a serious vaccine reaction as being equivalent to cancer, which is silly) from going unvaccinated.

> How many people actually die of cervical cancer before age 30?

4,462 young women under the age of 30 died of cervical cancer in 2022 worldwide [3].

[1] https://seer.cancer.gov/statfacts/html/cervix.html

[2] https://www.cancer.gov/news-events/cancer-currents-blog/2021...

[3] https://gco.iarc.who.int/today/en/dataviz/pie?mode=populatio... Mortality, cervix uteri, females, 0 to 29

Re: HPV vaccine cuts risk of dying from cervical cancer before 30

#7

Earlier quoted context omitted.

Your questions are sort-of answered in the article. 3300 die each year of cervical cancer in the uk. So at 0% it saves 3300 lives per year. However the vaccination is fairly new so they have to wait longer to see if it applies 20-years, 30-years, etc later. I assume it would though.

Parent's question isn't answered in the article - no figure is given for how many deaths under 30 there are as a baseline. From the article: “We estimate that since its introduction [in 2008], HPV vaccination has prevented nearly 200 young women from dying from cervical cancer in England.” This is an estimate of 200 total of any age total across 18 years. The article doesn't say 3300 die each year, 3300 are diagnosed…

The BBC article had that more comparable information: https://www.bbc.com/news/articles/c621z28z138o

> Between 2020 and 2024, no cervical cancer deaths were recorded in women aged 20 to 24 - the first time that had happened over a five-year period.

> Without vaccination, around 23 deaths would have been expected.

Note the first chart in the link showing the historical trend for the 20-24 cohort since 2000 plumetting from 25 to 0.

Re: HPV vaccine cuts risk of dying from cervical cancer before 30

#8
Just a note: the article focuses on the ladies, but men should absolutely get it as well because it cuts risk for other types of cancers. I was looking for a better link, however this is the only one I found (I had an older one saved, however I can't find it):

https://www.cnn.com/2026/04/24/health/hpv-men-vaccine-cancer...

Re: HPV vaccine cuts risk of dying from cervical cancer before 30

#10
post #5
post #2

From what risk level without them? How many people actually die of cervical cancer before age 30?? I mean, vaccinations and cancer prevention are both great, but this headline is ridiculous.

The estimated number of deaths from cervical cancer in the US in 2026 is 4,200. The death rate is 2.2 per 100,000 people down from 3.1 per 100,000 in 1992. If we multiply 3.1e-5 by 50 years that's about a 0.15% chance of dying of this cancer. The HPV shots cost $500-1000 for the three shots, so the cost per life saved is about $650K. With the statistical value of a human life being about $12M this is quite cost effec…

Even if you just consider all of those 4000 + survivors would have got treatment for the cancer after getting it which costs far more than a vaccine.
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