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Midjourney Medical

midjourney.com

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Re: Midjourney Medical

#302

> enough to give regular, monthly scans to a billion people. There is a part of me that thinks it would be cool to get cheap full body scans. I like being able to see inside of myself. I can think of a lot of situations where the low-fidelity images coming out of this (they're not good compared to real medical imaging, if you've ever looking at MRI/CT up close) could be useful for coarse analysis of certain condition…

This style of argument has always bothered me, because the correction to misdiagnosis or mistreatment is not to stop looking, it's _git gud_. For sure, we have to be realistic about what processes will systematically have error, and if we can't stop a doctor from doing bad things with a piece of data we should shield them from it, but the tools to make scalable, calibrated risk estimates based on large data dumps is…

No one is saying that we should stop looking. Especially not the commenter you replied to. They're saying the tech Midjourney presented isn't _gud_ enough to justify frequent scanning.

Re: Midjourney Medical

#303

Earlier quoted context omitted.

That's precisely where medicine is headed: personalized medicine. You [hopefully] won't have to become a rare missed diagnosis because you didn't fit the demographic for this or that screening test. Cost of genomic analysis is exponentially decreasing, and so much progress is happening so quickly. Consider for example how in cardiology we advanced from ASCVD's 10-yr prognosis, to the PREVENT 30-yr prognosis. And stil…

You’re dealing with populations here. Literally the odds of a positive being false would be over 90%. Much higher in the more rare conditions. I’m not exaggerating. That means every almost every follow up you do is a waste of time, money and limited resources, denying care to those who need it. Including you when you actually do need it. It also exposes you to the risks of unnecessary follow-ups like infection. Your…

It's scary in both directions.

If you let it give out tons of false positives, then patients are trained to ignore it when it cries wolf.

If you dial it back so that it gives out fewer positives, then now it starts giving out false negatives and not helping sick people.

Re: Midjourney Medical

#305

I think a lot of medical diagnosis could be solved with mass data collection if it was cheap enough. Right now, blood draws are somewhat routinely done because they provide a lot of human-interpretable indicators from a small number of values, and there is some evidence that e.g. "dogs can smell cancer" etc. (i.e. some diseases cause detectable odors). With a big enough data set of [all kinds of bio values, including…

It's a controversial and complicated idea. The downside, and the reason why most doctors do not recommend full body scans, is that every human body is a bit weird and there will almost always be something "wrong" that will be visible in a full body scan. This can lead to unnecessary testing, anxiety, and even unnecessary procedures. Many of these oddities flagged by the scan would never have caused any actual issues…

If the whole population had a full body scan every quarter, the “weird” things would feel more like the noise they are.

But we would have great data over time, both individually (weird tends to only matter if they are changing) and as a population.

Re: Midjourney Medical

#307

> enough to give regular, monthly scans to a billion people. There is a part of me that thinks it would be cool to get cheap full body scans. I like being able to see inside of myself. I can think of a lot of situations where the low-fidelity images coming out of this (they're not good compared to real medical imaging, if you've ever looking at MRI/CT up close) could be useful for coarse analysis of certain condition…

This style of argument has always bothered me, because the correction to misdiagnosis or mistreatment is not to stop looking, it's _git gud_. For sure, we have to be realistic about what processes will systematically have error, and if we can't stop a doctor from doing bad things with a piece of data we should shield them from it, but the tools to make scalable, calibrated risk estimates based on large data dumps is…

> This style of argument has always bothered me, because the correction to misdiagnosis or mistreatment is not to stop looking, it's _git gud_.

Exactly this. I mean, even if the scan is really indeterminate, at a minimum you can simply wait, then scan again. If it's truly something serious, it will become determinate at some point. Doing this is still better than nothing and carries no risks of unnecessary procedures.

Re: Midjourney Medical

#308

Earlier quoted context omitted.

Many smaht people have already pointed that out. It's news to no one that tests are imperfect. Do you have any concrete solution to that? Anything of value?

Yes, don’t do tests on asymptomatic low-risk people until you can demonstrate that a positive result has any meaning whatsoever.

Hypertension is asymptomatic for years and is prevalent in every demographic. Leaving it unattended it can cause stroke, heart attack, or organ damage through long-term vessel strain, by which time damage may be irreversible; detecting it on time can prevent this with lifestyle changes and medication.

Diabetes is asymptomatic for years and is prevalent in every demographic. Leaving it unattended it can cause damage to blood vessels, nerves, kidneys, and eyes through chronic high blood sugar, by which time complications may be advanced; detecting it on time can prevent or delay this with treatment and lifestyle changes.

Hyperlipidemia is asymptomatic for years and is prevalent in every demographic. Leaving it unattended it can cause artery blockage through cholesterol buildup, by which time heart attack or stroke may occur; detecting it on time can prevent this with diet and medication.

Kidney disease is asymptomatic for years and is prevalent in every demographic. Leaving it unattended it can cause kidney failure through gradual loss of function, by which time dialysis may be needed; detecting it on time can slow progression.

Glaucoma is asymptomatic for years and is prevalent in every demographic. Leaving it unattended it can cause irreversible vision loss through optic nerve damage, by which time blindness may be permanent; detecting it on time can preserve vision.

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I'm SO glad you're not my family doctor!

Re: Midjourney Medical

#309

I think a lot of medical diagnosis could be solved with mass data collection if it was cheap enough. Right now, blood draws are somewhat routinely done because they provide a lot of human-interpretable indicators from a small number of values, and there is some evidence that e.g. "dogs can smell cancer" etc. (i.e. some diseases cause detectable odors). With a big enough data set of [all kinds of bio values, including…

It's a controversial and complicated idea. The downside, and the reason why most doctors do not recommend full body scans, is that every human body is a bit weird and there will almost always be something "wrong" that will be visible in a full body scan. This can lead to unnecessary testing, anxiety, and even unnecessary procedures. Many of these oddities flagged by the scan would never have caused any actual issues…

I think the anodyne to this is - and I admit the degree to which this is indicative of my biases! - more data, especially early on. Getting a good baseline before you have really any significant chance of most cancers to be able to do within-individual diffs, effectively, might be a big deal.

It might also reveal that every MRI shows ghost artifacts a half a dozen times that make it longitudinally useless, of course. I'm not foolish enough to think that epidemiologists haven't thought of this.

Re: Midjourney Medical

#310
post #158

There are 100M pregnant women right now. If it works for just for the vanity use of seeing your baby grow (forget the medical imaging aspect) and can be as casual and relaxing experience as they put forward, then I can see such a spa being wildly successful.

is ultrasonic scanning completely harmless for developing baby? when my wife was pregnant, I remember they wouldn't recommend too frequent ultrasonic scans...

Ultrasound is totally harmless, but doctors recommend ALARA ("as low as reasonably achievable"). Average baby is exposed to 50 - 90 minutes of ultrasound over three visits, though we had to go more frequently for scans for all three of my kids. This would be 36 minutes if you went in every week. If it was possible to get medical quality anatomy scans and avoid transvaginal scans (either because of the tech or simply just going reguarly enough to catch all the imaging you need) then it would win the entire US market for sure: roughly $3-7B for the ultrasounds (3.5M US births at $1-2k per for ultrasounds). also it's a spa -- prenatal wellness spend in the US estimate at $5-7B.
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