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Making Claude a Chemist

anthropic.com

51–60 of 97 posts

Re: Making Claude a Chemist

#51

I feel like chemistry is one thing that current models will struggle with for the next while, because it's inherently 3D. In the micro world, shape = function. Maybe enough textual patterns will let it under chemistry, but like how do you describe a hydrogen shift without showing how it moves positions and rebalances bonds?

I wonder if chemistry skills will be an emergent behaviour of world model research.

Re: Making Claude a Chemist

#52

Let’s ban this before it gets too powerful !

I don't think it should be outright banned, automated intelligence is like a gun, hammer, knife, nuclear warhead, etc.

Ok I may agree with this. Instead to ban it we should nerf it to the point it’s useless.

Re: Making Claude a Chemist

#53
post #9

Earlier quoted context omitted.

> Even if you get the right molecule, it might be the wrong way around or just clump up into a useless mess. Sounds a lot like vibe coding lol

Modern biochemistry (so far) IS vibe coding lol. You mostly have vibes on how the chemistry should work, based on (very strong) natural evidence coupled with theoretical development and lab studies. Then you mix and match, goading bacteria and praying that they produce what you want in good measure. Then you take their secretions and run chromatography studies on them to check if that's what you actually want, or whe…

Or in some instances that "random bullshit" turns out to be something actually novel and/or useful.

Re: Making Claude a Chemist

#54

Earlier quoted context omitted.

I just wait until a Opensource model inhaled all the chemistry books and papers. Lol. They are following closely and the best offer 80-90% of the performance and come with a very small fraction of the costs.

Why wouldn't the US gov. outlaw the open source models?

Applicable to only those of the US (who choose to comply), which would mean giving non-US an advantage, which is a distinct no-no. They tried to restrict Fable to only-US, but that backfired since the world isn't at all clean cut, resulting in full unavailability of the model

Re: Making Claude a Chemist

#56

Earlier quoted context omitted.

Why wouldn't the US gov. outlaw the open source models?

Without international treaty and regulation restricting frontier capabilities globally, any attempt to outlaw open source models will only be as effective as King Canute ordering the tide to turn. Unless the USA fancies bombing those who refuse.

China is definitely refusing. And definitely will bomb back.

Re: Making Claude a Chemist

#57
post #6

The non-professional side of Organic Chemistry is one place where I think AI would really shine. Feels complex like solving a Rubik's cube to write down synthesis steps but it is all a sequence of memorized tricks. Do Cannizaro if you want this, Bergmann to do that. But the synthesis plan is only 10% of the actual work. The gap between writing down the synthesis step and actually doing it is also extremely large. Eve…

Hamilton Morris and his stuff on clandestine chemistry is super interesting in this domain. Sometimes the chemistry is straight forward but access to certain chemicals is hard, so the procedure must change based on what's available not necessarily what's ideal

Re: Making Claude a Chemist

#58

Earlier quoted context omitted.

I don't think it should be outright banned, automated intelligence is like a gun, hammer, knife, nuclear warhead, etc.

Ok I may agree with this. Instead to ban it we should nerf it to the point it’s useless.

Maybe nerf should start selling ai models.

Re: Making Claude a Chemist

#60
post #42

Earlier quoted context omitted.

you can already get that information by reading books in the library. The biggest barrier is not information, it's the ability to secure enough of the materials and equipment. For example, information for how to make a nuclear weapon is already there in the library. However, mining enough yellow cake and then purifying it is an industrial scale operation, out of reach unless you are a nation state, and have good moun…

> mining enough yellow cake and then purifying it is an industrial scale operation, out of reach unless you are a nation state or a transnational (or even national scale) energy and or minerals company. Might be hard to slip past the shareholders, but dark projects have flown under the annual reports of several large players.

Highly unlikely. Just the energy cost of running centrifuges, let alone manufacturing them is impossible to hide. It's staggering when you consider it.

To put some more perspective, an LLM could show you how to make a Boeing 747 in detail, but the actual chance of someone making one with no tools and logistics would be 0.

LLMs haven't changed the economic realities.

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