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Vibe coding my way to a healthy family: Introducing Gamow Labs

ddmckinnon.com

51–60 of 138 posts

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#51

Earlier quoted context omitted.

In what way?

lots of different ways, the loss of a child the potential loss of two children, the powerlessness and despair the parents would have been feeling... turning to AI which might have a positive outcome but many of us are not very trusting of the tool. Its a sad story. I wish them well, I hope this is one of those scenarios that AI works exactly as desired.

My technical take from this story was that human-run labs turned out to be less reliable than current AI.

This is the sort of performance/quality gap that is not obviously seen (who in the general population understands lab protocols in detail?) and could be massively improved with AI.

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#52
post #16

It reads like a specific genome would lead to deterministic outcomes. It does not. Life is messy. Most Down Syndrome people have happy lives, some can even live alone and have an independent daily live. Life expectancy is up to 60 years. Yet in Iceland „Democratization“ of genetic diagnosis lead to basically 0% Down Syndrome kids (births). Where does this stop? What with someone of a genetic indication of aggressive…

The toll it takes on parents and siblings, based on stories one reads, must be horrible.

You destroy the life of the family and greatly make the lives of healthy children harder.

Why would you sacrifice your healthy children for one who has no real future?

Complete inversion of common sense.

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#53

Earlier quoted context omitted.

In my country people with Down syndrome often live in housing together in suburban areas, with a social worker keeping an eye on things (independent living) or a carer available 24/7. They do sports, catch the bus, go to neighbourhood bbqs etc. Your depiction of a person with downs is not representative of the majority.

I’m fairly certain your depiction is not representative of the majority experience throughout the world. I can’t say for 100% certain but I struggle to believe what you’re describing is more common than not. That strikes me as a level of support provided by the state that most people with ds - and their family - do not enjoy throughout the world.

> I can’t say for 100% certain but I struggle to believe what you’re describing is more common than not.

This is absolutely common in New Zealand.

I think treating people with dignity, respect and part of the community is as important as state financial support.

Our government will also subsidise wages in certain industries for people with certain disabilities. So it’s common for people with intellectual disabilities to be working at supermarkets.

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#54

Earlier quoted context omitted.

I’m fairly certain your depiction is not representative of the majority experience throughout the world. I can’t say for 100% certain but I struggle to believe what you’re describing is more common than not. That strikes me as a level of support provided by the state that most people with ds - and their family - do not enjoy throughout the world.

> I can’t say for 100% certain but I struggle to believe what you’re describing is more common than not. This is absolutely common in New Zealand. I think treating people with dignity, respect and part of the community is as important as state financial support. Our government will also subsidise wages in certain industries for people with certain disabilities. So it’s common for people with intellectual disabilities…

Never questioned if it was common in New Zealand. I’m sure some countries have great support, and others do not. But in the aggregate, most people in the world simply do not have that level of support. So the conversation needs to be calibrated with that in mind.

Remember the original context here: someone talked about what they experienced and then you came in questioning it saying how wonderful the support you see is, then said what they experienced is not the majority experience, when the reality is quite the opposite actually. The support you are seeing is what is actually uncommon worldwide. New Zealand is exceptional here.

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#55
post #52
post #16

It reads like a specific genome would lead to deterministic outcomes. It does not. Life is messy. Most Down Syndrome people have happy lives, some can even live alone and have an independent daily live. Life expectancy is up to 60 years. Yet in Iceland „Democratization“ of genetic diagnosis lead to basically 0% Down Syndrome kids (births). Where does this stop? What with someone of a genetic indication of aggressive…

The toll it takes on parents and siblings, based on stories one reads, must be horrible. You destroy the life of the family and greatly make the lives of healthy children harder. Why would you sacrifice your healthy children for one who has no real future? Complete inversion of common sense.

"has no real future"?

I.e. not a net-productive member of society? Fun fact, machines are taking everything over, so you and any "healthy children" may be in that same camp very soon. IMO, anyone capable of living happily while being outcompeted by machines is well-adapted for the future.

I'm not; average Down's Syndrome folks seem to be.

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#56
post #23

My first son will be born in 2 months and I must say, between stories like this and others that I learned in antenatal classes - I have never been more terrified in my life

Good luck!

In case you find it useful, I wrote what I learned in my first year of fatherhood (the little guy is now 17 months): https://alejo.ch/3hj

As you can see, I never found anything as scary as the possibility, however remote, of my baby being unhealthy. So, yeah, best of luck!

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#57

Aside from the sad life events, little information is shares about his "system", the thing HN is interested in. Is this more than a harness built on top of a SOTA commercial LLM?

"the thing HN is interested in". Really though? We're talking about a deep human experience here. I don't know about HN as a whole but I personally come out of this much more touched about the human side of the story and how someone's life events can tremendously change their paths and goals than the LLM itself.

Same. And the insight of having used LLMs and it being so capable is a wtf moment for me in itself. And I am an AI engineer. It’s my job to have a good idea about how far these models can take us.

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#58

Earlier quoted context omitted.

Most cannot live alone and their parents have to take care about a huge, powerful 100 kg baby that needs constant attention until its death. My friend from elementary school has had a Down kid at 19. She takes it well, but managing a grown-up man five times as strong as her (she is petite) when he decides to do something like "take his bicycle and ride on a busy highway" is exhausting. This is why most people abort D…

In my country people with Down syndrome often live in housing together in suburban areas, with a social worker keeping an eye on things (independent living) or a carer available 24/7. They do sports, catch the bus, go to neighbourhood bbqs etc. Your depiction of a person with downs is not representative of the majority.

[deleted]

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#59

Earlier quoted context omitted.

I’m fairly certain your depiction is not representative of the majority experience throughout the world. I can’t say for 100% certain but I struggle to believe what you’re describing is more common than not. That strikes me as a level of support provided by the state that most people with ds - and their family - do not enjoy throughout the world.

> I can’t say for 100% certain but I struggle to believe what you’re describing is more common than not. This is absolutely common in New Zealand. I think treating people with dignity, respect and part of the community is as important as state financial support. Our government will also subsidise wages in certain industries for people with certain disabilities. So it’s common for people with intellectual disabilities…

New Zealand, probably among the bottom half of countries based on population, so quite likely what you’re describing is not the majority experience. It’s probably rather rare worldwide.

Re: Vibe coding my way to a healthy family: Introducing Gamow Labs

#60
post #41
post #38

Earlier quoted context omitted.

Such an inconsiderate and loaded question. Screening an embryo that could not survive outside the womb and deciding to stop the pregnancy based on the results is not the same as "wishing the kid wasn't born".

What are you talking about? Down Syndrom LE is 60 years.

And in some cases that means 60 years of support that needs to be provided. I can understand why some people would not choose that.
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