Not something to worry for the general population, but persons with genetic likelihood of getting Parkinsons should be wary of taking both Creatine and Coffee together. https://pmc.ncbi.nlm.nih.gov/articles/PMC4573899/
Creatine raises brain energy levels and slows cognitive decline: study
181–190 of 395 posts
Re: Creatine raises brain energy levels and slows cognitive decline: study
#182Earlier quoted context omitted.
Isn't 20+ grams a day a lot for the kidneys? genuine question
Elevated creatinine levels (in absence of supplementation) is a sign of kidney issues. There are many studies showing no reverse link i.e. supplementing creatine damaging kidneys https://link.springer.com/content/pdf/10.1186/s12882-025-045...
Okay but logically kidney issues leading to high creatine does suggest that creatine is not all that good for the body, no? else why would the kidney keep it under control?
Re: Creatine raises brain energy levels and slows cognitive decline: study
#183Peter Attia is a crap human being for being buddies with Epstein after most of his crimes were already known. But I still trust his analysis more than anyone else at dissecting this kind of stuff and separating the wheat from the chaff. I'll be curious to see if he covers this.
His website https://peterattiamd.com returns several direct creatine articles, podcasts, and AMAs with him and others.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#184All Men should be on creatine daily and lift weights a few times a week.
While this is true, but to my understanding this applies to women as well. Even one of these things has lots of benefits, but both are even better.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#185Side question: I've always been a recreational runner, running 3/4x a week, completed a few half marathons, and recently decided to _also_ go to the gym to do strength training as it has a lot of benefits for runners too. Should I consider/take creatine, is it useful?
Used to do something similar. If you intend to have any benefits of going to the gym then protein (and overall calorie consumption) would have to be monitored. Running sort of conflicts with working out: it wants you to be light and burns plenty of energy. Gym wants you to gain mass. No mass gains -> gym us useless. Creatine is kind of an afterthought in this bigger picture. Might give you an extra rep or two but tha…
Agree on getting enough protein (and sleep, and recovery time).
Strength training isn't all about mass. You can get stronger without gaining mass. There is a neural component and an efficiency component. At some point though you do need a bigger muscle to be stronger. There is also the question of whether you're optimizing for faster (fast twitch) or slower movements.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#186Since we are throwing in random N=1, it is very well tested and safe yes. But in my personal experience it does limit my creativity somehow. It seems to have like slightly calming/lower anxiety effect, and to me it comes with me coming up with fewer interesting things. Kind of lowering the model temperature if you will. Curious if anybody had a similar experience.
N=1 P=0.5
Re: Creatine raises brain energy levels and slows cognitive decline: study
#187Most of the human moods, energy levels, immunity, recovery, consciousness can be controlled by chemicals. It is no surprise that continuous use of a chemical will have impact.
The worry always is what does that extra chemical destroy as the body doesn't produce it naturally.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#188I'm 56 and have been experimenting with it. It definitely helps me stay laser focus on a task. I take between 10 to 15 grams a day in multiple doses. It does help with brain fatigue if you don't sleep well either. I'm also on keto diet and it helps me at the gym. Here is the thing everyone's DNA is different - keto works for me because I have tried it on and off. I have way more energy off carbs. I can also tolerate…
I’m still in the 30s but have found it to lower how much energy it takes to start something, rather than helping me stay focused. Same sort of idea, being in a higher-energy state, just pointing out that age doesn’t seem to be a requirement to get any benefit. I do also respond well the low-carb diets and heat that a lot from pro-creatine people so maybe there’s a connection to diet.
Re: Creatine raises brain energy levels and slows cognitive decline: study
#189Feedback about creatine often seems mixed. Many love it, but many also report problems. Just in this thread there are people talking about heart palpitations and sleep problems. I have the theory that these side effects and mixed experiences come from impurities of lesser quality products. Apparently there are mostly two sources: Creatine mono-hydrate which mostly comes from China and "creapure", which is a patented formula known for its purity. Does anyone have insight into how substantiated this theory is? How likely are negative effects because of pollutants/impurities?
Re: Creatine raises brain energy levels and slows cognitive decline: study
#190Most of the human moods, energy levels, immunity, recovery, consciousness can be controlled by chemicals. It is no surprise that continuous use of a chemical will have impact. The worry always is what does that extra chemical destroy as the body doesn't produce it naturally.
Creatine has been tested over long time spans already so this comment is not applicable here.
The better rebuttal is that the paper didn’t follow RCT protocols.