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Creatine raises brain energy levels and slows cognitive decline: study

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Re: Creatine raises brain energy levels and slows cognitive decline: study

#131

Post by vidarh »

laszlojamf wrote: post #79
ai_fry_ur_brain wrote: post #57

Earlier quoted context omitted.

This is a myth, its not bad for your kidneys. The reason this gets spread is because you will have higher levels of creatine in your urine if your Doctor tests your urine for kidney function, which indicates kidney disease. However, If you reveal to that doctor that you're supplementing Creatine it will not be concern them.

This has been my understand as well. I have CKD and my doctors have always been chill about it as long as I stop taking it about a week before having blood work done. EDIT: I don't do 25g though... sounds like a lot...

You're lucky your doctor is aware of it. I've had several who did not understand, and insisted creatine must be dangerous if it elevated creatinine levels, and/or didn't understand the effects.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#132

Post by stefs »

calibas wrote: post #70
el_benhameen wrote: post #49

Curious if anyone has had hair issues while taking it. I’m aware that there’s no positive evidence for an effect, but there is an at least plausible mechanism. I’ve gone through two periods where I took it and liked the effects, but felt like I shed way more hair and stopped due to that.

There's evidence creatine may raise DHT levels, and DHT causes hair thinning: https://pubmed.ncbi.nlm.nih.gov/19741313/

that study is widely regarded as unreliable and outdated.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#133

Post by Mistletoe »

davidmurdoch wrote: post #54
Mistletoe wrote: post #41

Earlier quoted context omitted.

I feel like it makes me feel like crap and my brain weird every time I try it and searching my spreadsheet shows this effect many times when I forget and read something like the above article and try it again. Anyone else feel like this?

> searching my spreadsheet What does this mean?

I keep a spreadsheet about my health, blood work, any supplements I take, how they make me feel etc. The summary would be that I take zero supplements now haha. I have tried so so many.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#134

Post by vidarh »

relevant_stats wrote: post #124
narmiouh wrote: post #22

Earlier quoted context omitted.

What did you use to determine this? Ask because many of the online tools I've tried, they will sometimes tag what I've written at 30-40% AI written and sometimes purely AI written stuff is flagged as 60-70% AI

As of now there are only two somewhat reliable tools. First one is Pangram. Other available detectors are varying level of bad, with some of them entirely shit (eg zerogpt something). The second one is human mind. Read enough of that slop and your brain hopefully will start detecting AI patterns. And this article is totally AI, both to Pangram, and to my mind.

My experience in testing actual AI written content on willing participants is that people are entirely useless at detecting AI written content with any reliability whatsoever.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#135

Post by AngryData »

king_zee wrote: post #33
cheschire wrote: post #12

Feels like a sign of the times that I expect half the comments here to be paid astroturfing about how amazing creatine is.

I work out but I've never taken it. I feel like not everything has to be minmaxed, sometimes some things are better left to nature. Easy come easy go as they say

Also a lot of peoples diets have a high amount already. And certain things like energy drinks have a lot if you drink a those.

I think a lot of the minmaxed stuff people do working out is mostly placebo because very few people are actually pushing the limits of natural human physiology and hitting some nutrient bottleneck.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#137

Post by Insanity »

ai_fry_ur_brain wrote: post #57
gardnr wrote: post #37

Earlier quoted context omitted.

Just in case anyone is thinking about trying it: 25g seems pretty high. It’s worth it to review what that means for the rest of your body before starting this regime. Kidneys are really useful organs to have working.

This is a myth, its not bad for your kidneys. The reason this gets spread is because you will have higher levels of creatine in your urine if your Doctor tests your urine for kidney function, which indicates kidney disease. However, If you reveal to that doctor that you're supplementing Creatine it will not be concern them.

At the risk of sounding stupid. Doesn’t this mean it would mask actual kidney disease? So you’d be ignoring potential warning signs.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#138

Post by fer »

zug_zug wrote: post #58
WhitneyLand wrote: post #36

The article made up the claim it’s not from the paper itself. There was some improvement in cognitive scores, but no placebo group. Without a placebo group, there are a lot of explanations for the data.

>> Recently, a pilot study (single-arm) by Smith et al., recruited 20 patients (73 years of age) with AD and provided them with 20 grams/day of CrM for 8 weeks [20]. Serum creatine levels were increased at weeks 4 and 8 (p Yeah 20 patients is not a lot. I'm inferring this is a pre-post test. However some of those p-values are pretty good (.001 on reading and and sorting). Very promising pilot study but not conclusive…

.001 for creatine levels isn't surprising; that's a lot of creatine. I'd explain the cognitive tests with the practice effect, because it is unlikely that creatine had such a massive effect and we only discover it now.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#139

Post by vkazanov »

noisy_boy wrote: post #77
zug_zug wrote: post #67

Earlier quoted context omitted.

Do you work out? If so creatine is supposed to help people push themselves harder and thus build more muscle. As a side-effect of intense exercises you'll create more testosterone. Increased testosterone leads to balding.

Sometimes when I see muscular guy with a head full of hair, I wonder what is counteracting that increased testosterone.

Sometimes people just have good hair and spend a lot of time in the gym.

Even early 90s famous era mass monsters were not all bald.

Baldness is known to be related to a bunch of things: testosterone levels, something to do with blood delivery to the scalp, deeper genetic factors.

Surprsingly, for some of the cases scalp massage is known to help.

Re: Creatine raises brain energy levels and slows cognitive decline: study

#140

Post by Insanity »

iwontberude wrote: post #112
ai_fry_ur_brain wrote: post #62

Earlier quoted context omitted.

Its changed my life. Im also a long time vegan with MTHFR gene mutations and sleep issues though.

That’s a pretty amazing acronym if real

Say MTHFR one more time, I dare you.

Never heard of the acronym though so not sure what the mutation implies.

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