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Not alive, but not dead: disembodied human brains used for drug testing

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Re: Not alive, but not dead: disembodied human brains used for drug testing

#182
post #60

Earlier quoted context omitted.

When I had my ear surgery about 20 years ago, the doctor explained to me that I would be awake for part of the procedure, but the anesthesia meant that I would have no memory of it.¹ It’s a weird thing to think about whether that lack of memory would obviate the pain or discomfort of the moment. ⸻ 1. As it turned out, I was so frightened in the lead-up to the surgery that they had to do general anesthesia on me becau…

Oh yeah, I've had two cath lab visits. In both of them, I woke up in the middle of the process, conscious enough to recognize that the black-and-white image on the screen was me with a wire in my heart and little puffs of dye. The first time it happened, I was fascinated watching the process. I thought I asked them a question about what I was seeing. I probably was just mumbling. The second time, I had a bright white…

I'm in the UK and was intentionally kept conscious during angioplasty and stent placement. Mind you, it was an emergency heart-attack kind of appointment! The experience was very cool and I recall that the wire-wriggling cardiologist wore a sectional lead suit (rapidly firing X-ray machine) and to my drug-addled brain, reminded me of the armored gorillas in the Planet of the Apes movies.

Re: Not alive, but not dead: disembodied human brains used for drug testing

#183
post #60

Live dissection and experimentation on “alive but drugged” human brains is mental. How do you ensure that you aren’t torturing a brain that can’t see, hear or scream? How are you held accountable?

When I had my ear surgery about 20 years ago, the doctor explained to me that I would be awake for part of the procedure, but the anesthesia meant that I would have no memory of it.¹ It’s a weird thing to think about whether that lack of memory would obviate the pain or discomfort of the moment. ⸻ 1. As it turned out, I was so frightened in the lead-up to the surgery that they had to do general anesthesia on me becau…

I had a low stakes cyst removal from my butt crack once. Sparing the other details, the anesthesiologist explained the different drugs, one to numb, one to prevent my memory from forming. I asked if they could leave out the memory drug and I could remain cognizant. She didn't mind and I had a nice chat with her about anesthetics while on my stomach having doctors cut out part of my butt.

Re: Not alive, but not dead: disembodied human brains used for drug testing

#185
post #60

Earlier quoted context omitted.

When I had my ear surgery about 20 years ago, the doctor explained to me that I would be awake for part of the procedure, but the anesthesia meant that I would have no memory of it.¹ It’s a weird thing to think about whether that lack of memory would obviate the pain or discomfort of the moment. ⸻ 1. As it turned out, I was so frightened in the lead-up to the surgery that they had to do general anesthesia on me becau…

I had the same thoughts "but won't i feel it THEN?" when I was getting an upper endoscopy. The anesthesiologist said you're in such a trance, dreamlike state plus with the inability to form memories its like you're not your real "consciousness" but something different. Sort of like your brain is in "limp mode" and its not really _you._ This was both comforting and slightly terrifying in a different way.

I do remember my lung biopsy where they went in down my neck. Maybe they give less drugs for that than for your upper endoscopy. My memories have a slightly horror movie vibe but I would not be put off having the procedure again.

Re: Not alive, but not dead: disembodied human brains used for drug testing

#186
post #156

This is legal but I can't legally pay another adult for sex or take drugs that could harm me? And there are many restrictions on gambling. It's weird how some morals are legislated but not others.

All you mentioned can have negative side effects for third parties.

Disagree

Re: Not alive, but not dead: disembodied human brains used for drug testing

#187
post #156

This is legal but I can't legally pay another adult for sex or take drugs that could harm me? And there are many restrictions on gambling. It's weird how some morals are legislated but not others.

All you mentioned can have negative side effects for third parties.

Compared to legal and regulated drugs? Rarely.

Re: Not alive, but not dead: disembodied human brains used for drug testing

#188
post #134

Earlier quoted context omitted.

I highly highly doubt that by consenting to be an organ donor you are consenting to this. Unless you live in some incredibly lawless country? Organ donation is so very sensitive, and those who use the service are so aware of the sensitivities I think that you'd be insane to have such a reaction to this media piece. In fact, I'll go one further. I have serious doubts you were ever an organ donor at all.

Your doubts are solidly founded; I can confirm I am not yet dead and my organs have not yet been donated.

You wouldn't know if we simulated you well enough.

Re: Not alive, but not dead: disembodied human brains used for drug testing

#189
post #165

Earlier quoted context omitted.

> It's still an open debate No it's not, not by anyone serious. We know the brain is the seat of consciousness because damage to the brain damages consciousness. There is no other organ in the body where that's true. You can completely replace all other organs without changing consciousness. You can always find a paper by a quack that posits the earth is flat, that doesn't mean there's serious debate.

Can you point me to a paper or other source that proves that the brain is the seat of consciousness? Or that disproves other theories? I am familiar with the works of Oliver Sacks, Paul Broks, and others, who have spent their lives researching damage to brains and the potential consequences for the psyche. I agree that it sounds like damage to the brain can have big impact, but none of that research, as far as I am a…

Ok, I've actually read into the 3 articles you've suggested and none of them are making the argument you are making. I think you just title mined.

Article 1. is about how the brain interprets incoming signals from the body

Article 2. is about dealing with psychiatric needs, such as medication compliance and stress, which result from organ transplants.

And, as I addressed in another comment, Article 3. is a discussion about the impacts of gut microbiome on mood. It is not a discussion of "consciousness".

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