It makes me incredibly sad that people are willing to stare straight ahead at a fucking lightbulb (a.k.a. sites with a white background) and destroy their vision.
Most probably is due to a non-optimal screen both at home and work-place, but I suffer from the same issue even on 2010 iMacs.
But the most pleasant scheme for me (I mean, my eyes) is light-gray-on-dark-gray.