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Fecal transplants for autism deliver success in clinical trials (2019)

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Re: Fecal transplants for autism deliver success in clinical trials (2019)

#191

Post by krisoft »

kjkjadksj wrote: post #152
jodrellblank wrote: post #146

Earlier quoted context omitted.

How is one judging a "gut ecosystem collapse" from toilet visits?

Loose and unsatisfying stool?

How do you know that is a “gut ecosystem collapse” as opposed to hypermotility? Or an overgrowth of the gut ecosystem? Or a problem with the intestinal lining?

Observing that if you eat/drink something specific then you get the shits is valid. Concluding that it is due to a specific mechanism is not valid unless you have something objective like a test supporting that.

It’s like if your train is late and you just conclude that it must be because the steam condenser’s gasket is leaking based on nothing. Maybe true, or maybe the conductor broke his leg, or there is a signaling failure.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#192

Post by simulator5g »

Muromec wrote: post #17
geremiiah wrote: post #14

What's more plausible? Did they cure low functioning autism in two years? Or did they simpily miscategorize the kids and the kids grew out of their diagnosis as they matured?

Kids got into tech industry and now it’s their spouses that have to deal with their tism, instead of parents

its alright bub some of us autists thought it was funny

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#193

Post by simulator5g »

Balgair wrote: post #85
tt_dev wrote: post #76

Title is a bit misleading. It’s not a fecal transplant. It’s tablets and powder (for the pitt-hopkins cases) of microbes from fecal donors. Consumes orally. More like fecal food?

What did you think a fecal transplant was?

I mean the word transplant implies that it does not go in the mouth. Unless the patient uh... does things a little differently.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#194

Post by simulator5g »

andy_ppp wrote: post #89

AFAIK fecal transplants do not work well long term, has there been any research in making them more sticky? Lots of things you could trial but I have a feeling it’s the immune system responding to the right bacteria incorrectly…

The bacteria in your gut come from food, the long-term fix is to eat a better diet. Unfortunately, this is quite confusing for most people because you can't see the microbiome in your food, and the only practical way to sense what kinds of bacteria you're promoting with your diet, is to ask yourself "how do you feel" which can be affected by all sorts of unrelated things. I mean, most people don't even really think about how they feel, they wouldn't be able to answer the question.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#195

Post by bodiekane »

delecti wrote: post #145
SoftTalker wrote: post #110

Earlier quoted context omitted.

Doesn't seem like something that would require an inpatient stay.

> [...] the treatment, which involved a bowel cleanse and daily transplants of fecal microbiota over a period of seven to eight weeks Maybe I'm misinterpreting what the process of that daily transplant looked like, but I expect they ate a not insignificant amount of hospital food if there were 7-8 weeks of daily treatments.

Ya, the word "transplants" here seems to mean something very different than you're interpreting it as.

This isn't a hospital procedure like an organ transplant. It's material placed into the recipients colon through an enema, nasogastric tube or possibly even just taking some pills.

So it might range from done at home to done during a 30 minute visit to a clinic.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#196

Post by [deleted] »

dimes wrote: post #70
directevolve wrote: post #56

Many autistic children have extremely limited diets. For example, a geneticist friend of mine saw a case where an autistic child had been referred for genetic testing because of horrific, chronic, spontaneous wounds on gums and skin. Turned out to be scurvy, because he had exclusively eaten Wheat Thins for the last 3-4 years, which aren’t fortified with vitamin C. I would fully expect that a monotonous diet leads to…

Just to play devil’s advocate, isn’t it also possible that the preference for a monotonous diet is driven by gut makeup?

[deleted]

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#197

Post by Muromec »

dacops wrote: post #53
Muromec wrote: post #17

Earlier quoted context omitted.

Kids got into tech industry and now it’s their spouses that have to deal with their tism, instead of parents

Buzz off. If you were trying to make a joke, it didn't land. It scans as ableist twat.

Which part of this you think is a joke?

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#198

Post by Muromec »

firstbabylonian wrote: post #52
Muromec wrote: post #17

Earlier quoted context omitted.

Kids got into tech industry and now it’s their spouses that have to deal with their tism, instead of parents

Self-hatred is not a good look.

That's a very privileged Westerner opinion to have.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#199

Post by mtizim »

sleight42 wrote: post #162
Muromec wrote: post #17

Earlier quoted context omitted.

Kids got into tech industry and now it’s their spouses that have to deal with their tism, instead of parents

This is incredibly offensive. Mods, please see to this comment.

Why? I have mild tism, I found it quite funny and quite real, it even felt good to be seen.

Re: Fecal transplants for autism deliver success in clinical trials (2019)

#200

Post by malfist »

kjkjadksj wrote: post #152
jodrellblank wrote: post #146

Earlier quoted context omitted.

How is one judging a "gut ecosystem collapse" from toilet visits?

Loose and unsatisfying stool?

With IBS-D every meal can result in a loose and unsatisfying stool output! Don't ask me how I know. GLP-1s actually make a hell of a difference for me.
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