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Venom and hot peppers offer a key to killing resistant bacteria

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Re: Venom and hot peppers offer a key to killing resistant bacteria

#81

Post by metalman »

eth0up wrote: post #37

I have struggled with various infections over the last 15 years. One of them, among the worst being h-pylori. Of all these infections, I've been forced, due to absence of healthcare and aversion to the medical industry in general, to treat myself across the board. H Pylori is a very interesting subject, deeply misunderstood until a certain Australian hero brute forced through the arrogance of the day by infecting him…

recently here, there was an article suggesting that combining hot chilies, with mint, acentuated the anti inflamitory effects of capsaicin by 100 times, and reminds me that I was waiting for my mint to come up, which it will most definitly have done, and I have fresh chillies so the bar is very very low to try it for taste, if nothing else.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#84

Post by RataNova »

charliebwrites wrote: post #4

If you’ve ever wondered why the symbol of health is a snake spiraling a staff (the Greek god Asclepius’s staff to be specific), it’s because in Ancient Greece they used small amounts of snake venom to treat serious illnesses We’ve come full circle

Medicine has always borrowed from biology's more dangerous toolkit

Re: Venom and hot peppers offer a key to killing resistant bacteria

#85

Post by RataNova »

jjk166 wrote: post #60

I imagine the long term solution to antibiotic resistance are engineered bacteriophages, either to directly attack the bacteria or to insert genes that make the bacteria susceptible to specific agents. Beyond not having to continuously develop new antibiotics or restrict treatment, these could also be much more targeted treatments with less harmful effects on a patient's microbiome. Of course scaling up to mass produ…

I agree phages are probably part of the answer

Re: Venom and hot peppers offer a key to killing resistant bacteria

#86

Post by jolt42 »

Ar-Curunir wrote: post #71
jolt42 wrote: post #16

Earlier quoted context omitted.

I always assumed what I felt was obvious: Numbers 21:4-9, where God instructs Moses to make a bronze serpent and place it on a pole to heal Israelites dying from poisonous snake bites.

But the symbol is explicitly non-abrahamic in origin…

And yet the similarities can't be coincidental. Rod + Snake = Life Saving.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#87

Post by MrFots »

jolt42 wrote: post #16
charliebwrites wrote: post #4

If you’ve ever wondered why the symbol of health is a snake spiraling a staff (the Greek god Asclepius’s staff to be specific), it’s because in Ancient Greece they used small amounts of snake venom to treat serious illnesses We’ve come full circle

I always assumed what I felt was obvious: Numbers 21:4-9, where God instructs Moses to make a bronze serpent and place it on a pole to heal Israelites dying from poisonous snake bites.

The Christian Bible is not a historical document.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#88

Post by fakedang »

cubefox wrote: post #46
fakedang wrote: post #33

Earlier quoted context omitted.

It depends - if someone uses the same compound but provably for a different indication (like maybe anti-periodontic diseases or something) or for a different intake mechanism, they could get another patent and proceed with trials. Granted, it's not going to be easy because the original patent has expired so it's going to be very easy for an upstart Indian company to conduct basic clinical trials, use part of the data…

Anti-periodontic diseases are highly irrelevant compared to cavities. Not even the original cavity application did manage to get enough funding at the time. So there will be no Indian upstart, there is and likely will be nobody who invests the money into ultra expensive trials. The ship has sailed.

I wasn't trying to quote a directly applicable example, just wanted to illustrate a potential pathway for post-expiry commercialization.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#89

Post by jolt42 »

MrFots wrote: post #87
jolt42 wrote: post #16

Earlier quoted context omitted.

I always assumed what I felt was obvious: Numbers 21:4-9, where God instructs Moses to make a bronze serpent and place it on a pole to heal Israelites dying from poisonous snake bites.

The Christian Bible is not a historical document.

That wouldn't prevent the caduceus from being based on the story.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#90

Post by Ar-Curunir »

jolt42 wrote: post #86
Ar-Curunir wrote: post #71

Earlier quoted context omitted.

But the symbol is explicitly non-abrahamic in origin…

And yet the similarities can't be coincidental. Rod + Snake = Life Saving.

Not sure what you’re trying to say? That the Greeks got it from a Semitic people? Or something else?
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