If you’ve ever wondered why the symbol of health is a snake spiraling a staff (the Greek god Asclepius’s staff to be specific), it’s because in Ancient Greece they used small amounts of snake venom to treat serious illnesses We’ve come full circle
Venom and hot peppers offer a key to killing resistant bacteria
41–50 of 92 posts
Re: Venom and hot peppers offer a key to killing resistant bacteria
#42Earlier quoted context omitted.
Funnily enough, my wife is Mexican and I think I have a higher tolerance for spicy food than she does. She won't even do the Taco Bell Fire Sauce.
That is a bit suspicious. How accurate is she with the chancla at long range?
Re: Venom and hot peppers offer a key to killing resistant bacteria
#43Hats off, not only were they able to isolate just two molecules, but also established that they were colorless.
I don't think this is a usual definition for benzoquinones:
"heterocyclic compounds that do not contain amino acids".
I can smell Sam Altman's socks reading this article.
Re: Venom and hot peppers offer a key to killing resistant bacteria
#44Earlier quoted context omitted.
We also recently (we think) discovered why acupuncture works. That form of medicine from 4000 years ago...
There’s also electroacupuncture, which is gaining popularity in physical therapy clinics in the US. > Like traditional acupuncture, electroacupuncture uses needles placed in the same spots. Then, a small electrode is attached to the needles. A small amount of electricity runs through the electrode and gives a slight vibration or soft hum during treatment. (1) Since they use the same spots as traditional acupuncture e…
It's just relying on poking stuff with needles to improve the blood flow.
Re: Venom and hot peppers offer a key to killing resistant bacteria
#45"Researchers have developed", yeah. When I read such things, I always recall https://en.wikipedia.org/wiki/Epimerox - this thing promised wonders - very broad spectrum, very low toxicity - and, most importantly, it was targeting a conservative essential protein - so nearly zero resistance. And there were no updates for more than a decade. Something developed in a lab is something we, most likely, will never see - and…
This one is quite tinfoil-hat inspiring, as the research was moved to defense-focused Draper Labs and then immediately disappeared.
Re: Venom and hot peppers offer a key to killing resistant bacteria
#46Earlier quoted context omitted.
Similar thing, permanent anti-cavity bacteria: https://www.cremieux.xyz/p/the-rise-and-impending-fall-of-th... The patents expired, so nobody can raise the hundreds of millions to do the phase II/III safety trials.
It depends - if someone uses the same compound but provably for a different indication (like maybe anti-periodontic diseases or something) or for a different intake mechanism, they could get another patent and proceed with trials. Granted, it's not going to be easy because the original patent has expired so it's going to be very easy for an upstart Indian company to conduct basic clinical trials, use part of the data…
Re: Venom and hot peppers offer a key to killing resistant bacteria
#47Earlier quoted context omitted.
This story actually checks out, which is quite the condemnation of our American drug development system. One thing bugs me though - why don't other countries with different research structures pick this up and run with it?
> This story actually checks out, which is quite the condemnation of our American drug development system. Oh yeah, "corporations", "end-stage capitalism", blah blah. The reality is that 95+% of drug candidates fail the trials. And a lot of them only fail during the Phase-3 where the efficacy is tested. It's likely that large companies tried it in-house and found that it's either too toxic or is ineffective in-vivo.
Re: Venom and hot peppers offer a key to killing resistant bacteria
#48"Researchers have developed", yeah. When I read such things, I always recall https://en.wikipedia.org/wiki/Epimerox - this thing promised wonders - very broad spectrum, very low toxicity - and, most importantly, it was targeting a conservative essential protein - so nearly zero resistance. And there were no updates for more than a decade. Something developed in a lab is something we, most likely, will never see - and…
Is this particular drug head and shoulders above other candidates? Is it possible that the reason it hasn't gotten attention is because researchers have been looking at other cheaper or more promising candidates? (I do not know, I am genuinely asking.)
Re: Venom and hot peppers offer a key to killing resistant bacteria
#49If you’ve ever wondered why the symbol of health is a snake spiraling a staff (the Greek god Asclepius’s staff to be specific), it’s because in Ancient Greece they used small amounts of snake venom to treat serious illnesses We’ve come full circle
I thought it’s a stick to pull out a tape worm. You wrap it around the worm and keep twisting to get it out.
Re: Venom and hot peppers offer a key to killing resistant bacteria
#50I am addicted to hot peppers. What I do in the morning is get one Scotch Bonnet (or two smaller ones), two oranges, lime and a piece of ginger into a cold press and then drink it in one go. Can't describe it exactly, but it's like being transported to another dimension for a few seconds, then there is pain, then there is relief and then a nice warm feeling in the belly.
So yeah no more peppers without rice for me.