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Venom and hot peppers offer a key to killing resistant bacteria

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Re: Venom and hot peppers offer a key to killing resistant bacteria

#21
I am addicted to hot peppers. What I do in the morning is get one Scotch Bonnet (or two smaller ones), two oranges, lime and a piece of ginger into a cold press and then drink it in one go.

Can't describe it exactly, but it's like being transported to another dimension for a few seconds, then there is pain, then there is relief and then a nice warm feeling in the belly.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#23

I am addicted to hot peppers. What I do in the morning is get one Scotch Bonnet (or two smaller ones), two oranges, lime and a piece of ginger into a cold press and then drink it in one go. Can't describe it exactly, but it's like being transported to another dimension for a few seconds, then there is pain, then there is relief and then a nice warm feeling in the belly.

I too am addicted to hot peppers. But doesn't this... IDK, it seems like it would mess up my stomach or esophagus lining or something. All that acid and capsaicin on an empty stomach?

Re: Venom and hot peppers offer a key to killing resistant bacteria

#25

"Researchers have developed", yeah. When I read such things, I always recall https://en.wikipedia.org/wiki/Epimerox - this thing promised wonders - very broad spectrum, very low toxicity - and, most importantly, it was targeting a conservative essential protein - so nearly zero resistance. And there were no updates for more than a decade. Something developed in a lab is something we, most likely, will never see - and…

This story actually checks out, which is quite the condemnation of our American drug development system.

One thing bugs me though - why don't other countries with different research structures pick this up and run with it?

Re: Venom and hot peppers offer a key to killing resistant bacteria

#26
post #17
post #6

Earlier quoted context omitted.

We also recently (we think) discovered why acupuncture works. That form of medicine from 4000 years ago...

There’s also electroacupuncture, which is gaining popularity in physical therapy clinics in the US. > Like traditional acupuncture, electroacupuncture uses needles placed in the same spots. Then, a small electrode is attached to the needles. A small amount of electricity runs through the electrode and gives a slight vibration or soft hum during treatment. (1) Since they use the same spots as traditional acupuncture e…

I read a paper that basically said that the spot itself didn't matter so much, that part was voodoo, but the needling produced a response from your body that helped.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#27
post #9

Earlier quoted context omitted.

Do you happen to have a source for that? I’d love to check it.

It's the New York Times article that's linked to in this HN post about “the Interstitium”: https://news.ycombinator.com/item?id=48095536

Radiolab did a show on that a couple years ago. Pretty interesting listen.

https://radiolab.org/podcast/interstitium

They also did an episode about rapamycin that I thought was really cool. I had no idea the history of it and found it fascinating and it really gets the imagination going thinking about what other things are hidden all around us.

https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub

Re: Venom and hot peppers offer a key to killing resistant bacteria

#28

"Researchers have developed", yeah. When I read such things, I always recall https://en.wikipedia.org/wiki/Epimerox - this thing promised wonders - very broad spectrum, very low toxicity - and, most importantly, it was targeting a conservative essential protein - so nearly zero resistance. And there were no updates for more than a decade. Something developed in a lab is something we, most likely, will never see - and…

It was pretty common for message board users to come together to do group buys for novel research chemical synthesis 15-20 years ago. Not sure why things like this would be any different.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#29

"Researchers have developed", yeah. When I read such things, I always recall https://en.wikipedia.org/wiki/Epimerox - this thing promised wonders - very broad spectrum, very low toxicity - and, most importantly, it was targeting a conservative essential protein - so nearly zero resistance. And there were no updates for more than a decade. Something developed in a lab is something we, most likely, will never see - and…

This story actually checks out, which is quite the condemnation of our American drug development system. One thing bugs me though - why don't other countries with different research structures pick this up and run with it?

I agree... Medication Resistant bacteria is a problem everywhere. There's probably no money in a new antibiotic, but... Having something new to fight TB would be nice, and there's still prestige, even if you "just" brought it to market and didn't discover it.

I would think there are pharma teams in China or India, maybe even Russia that could replicate and further develop something like this, given the initial paper and PR.

Re: Venom and hot peppers offer a key to killing resistant bacteria

#30

I am addicted to hot peppers. What I do in the morning is get one Scotch Bonnet (or two smaller ones), two oranges, lime and a piece of ginger into a cold press and then drink it in one go. Can't describe it exactly, but it's like being transported to another dimension for a few seconds, then there is pain, then there is relief and then a nice warm feeling in the belly.

I too am addicted to hot peppers. But doesn't this... IDK, it seems like it would mess up my stomach or esophagus lining or something. All that acid and capsaicin on an empty stomach?

I've been doing this for like two years now and see no adverse effects, but that is just me.
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