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Notes from the SF peptide scene

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Re: Notes from the SF peptide scene

#121

Post by greygoo222 »

Aurornis wrote: post #6

This article is an anecdote extrapolated to something bigger: A type of lazy writing where the writer has a single social experience with a group of weird people and then writes about it like it’s the common experience in a place. The writer went to SF for a few days and went to one party where a group of friends were into peptides. From the article, they were also particularly terrible people. Just read this quote:…

If someone wants to take Ozempic for cosmetic reasons, that's their business. I am almost certain you personally indulge in riskier activities than using Ozempic, or... modafinil? You know people still use research chemicals, testosterone, and modafinil, right?

Re: Notes from the SF peptide scene

#122

Post by keane »

JuniperMesos wrote: post #116
Havoc wrote: post #57

Kinda wild to me that people are down with injecting mystery substances received from the other end of the world entirely outside any real medical chain or certainty of contents or recourse. Like black market steroids except with less track record

The health problems associated with obesity are very real (not to mention that it makes you look worse), GLP-1 agonists really do work for most people to cause significant weight loss, and it's currently difficult to get them prescribed by a legitimate doctor unless your obesity-related health problems are really severe. This will probably change over the next several years, but in the meantime buying them from a gre…

There’s a good three part radio series from the Center for Investigative Reporting and PRX about how drugs for pets sourced from grey markets played out with the FDA:

[index] https://revealnews.org/podcast/cat-drug-feline-infectious-pe...

[1] https://www.hyperfixedpod.com/listen/hyperfixed/the-cat-drug...

[2] https://www.hyperfixedpod.com/listen/hyperfixed/the-cat-drug...

[3] https://www.hyperfixedpod.com/listen/hyperfixed/the-cat-drug...

Re: Notes from the SF peptide scene

#123

Post by dcrazy »

alexjplant wrote: post #67
ambicapter wrote: post #4

I think this author has a very different conception of what “sincerity” is than I do, but I guess that’s the difference between the east coast and the west coast.

From TFA: > Someone once said that SF is a town of extremely high sincerity, and all of its modern and historical weirdness — the AI doomerism, the cults, the hippies, the drug use, the polycules — is downstream of people saying things and other people taking them extremely seriously. This is a perfectly reasonable usage - perhaps not the Hallmark greeting card one but it's certainly valid. > the difference between t…

When a New Yorker says “east coast,” they mean “the New York City metro area.” Everywhere else is referred to by name.

Re: Notes from the SF peptide scene

#124

Post by mh2266 »

EvanAnderson wrote: post #112
mh2266 wrote: post #50

WTF is any of this, is there some ELI5/OOTL explanation? I work in big tech and have never heard anyone talk about "peptides". Is this a startup scene thing or just an SF thing? (I live in New York) all of my coworkers are pretty normal, sure there are the stereotypical fitness types that are marathon training, cycling, or have a climbing gym membership but no one is talking about buying weird Chinese drugs

I'm in western Ohio and had heard about the peptide fervor on podcasts but never IRL. Today, at my daughter's soccer game, I overheard a long conversation between two guys in their mid-40s comparing their peptide regimens (along with just discussing their fitness activities). I'd never actually heard anybody talk about it before. At first it was the generic CrossFit talk I'm used to hearing, then to diet and recovery…

> It sounded like both of them are injecting themselves from stuff they're buying on the Internet.

lol, wtf. I mean, I am a moderately serious cyclist, I guess (~250 miles/week) and also climb, hike, other outdoors sports etc. So I do care about performance and diet and such. But there is zero chance I am sticking a needle full of something I bought on the internet into myself—what on earth?

Re: Notes from the SF peptide scene

#126

Post by jliptzin »

Havoc wrote: post #57

Kinda wild to me that people are down with injecting mystery substances received from the other end of the world entirely outside any real medical chain or certainty of contents or recourse. Like black market steroids except with less track record

Not sure what is so surprising. People take health advice from comedian podcasters these days. RFK Jr is HHS Secretary. Maybe 10 years ago this would be wild, but today it is completely and utterly unsurprising.

Re: Notes from the SF peptide scene

#127

Post by trogdor »

JuniperMesos wrote: post #116
Havoc wrote: post #57

Kinda wild to me that people are down with injecting mystery substances received from the other end of the world entirely outside any real medical chain or certainty of contents or recourse. Like black market steroids except with less track record

The health problems associated with obesity are very real (not to mention that it makes you look worse), GLP-1 agonists really do work for most people to cause significant weight loss, and it's currently difficult to get them prescribed by a legitimate doctor unless your obesity-related health problems are really severe. This will probably change over the next several years, but in the meantime buying them from a gre…

> it's currently difficult to get them prescribed by a legitimate doctor unless your obesity-related health problems are really severe

I think it’s more accurate to say that it’s difficult to get them covered by insurance unless your obesity-related health problems are really severe. In my experience, doctors have no problem prescribing GLP-1 drugs for weight management.

Re: Notes from the SF peptide scene

#129

Post by mh2266 »

negura wrote: post #117
mh2266 wrote: post #50

WTF is any of this, is there some ELI5/OOTL explanation? I work in big tech and have never heard anyone talk about "peptides". Is this a startup scene thing or just an SF thing? (I live in New York) all of my coworkers are pretty normal, sure there are the stereotypical fitness types that are marathon training, cycling, or have a climbing gym membership but no one is talking about buying weird Chinese drugs

this was formely the fanbase of the dark enlightenment movement. an avantgarde techno-capitalist alt-right underground culture. Musk, Thiel, a16z, Altman, Srinivasan, many in the Trump administration (including Vance) have acknowledged their involvement with it. the ideological underpinnings are mainly given by two philosophers/bloggers: nick land and curits yarvin. the rest of the people at those parties are like a…

> this was formely the fanbase of the dark enlightenment movement. an avantgarde techno-capitalist alt-right underground culture.

https://giphy.com/gifs/no-ji6zzUZwNIuLS

> Edit: New York had pretty much the same thing, called the Dimes Square movement. it was linked to the controversial remilia/milady NFT collection

https://giphy.com/gifs/no-ji6zzUZwNIuLS

thanks for the articles...

Re: Notes from the SF peptide scene

#130

Post by bradlys »

Sincerely hope this guy keeps his day job. I couldn’t be bothered to do more than skim a few paragraphs.

This is from someone who has a dozen peptides in his freezer, gives them to friends, and is on them as well. You’d think I would be interested in reading an article that is supposed about “me”. I am not in the rationalist peptide space though. Find these guys to be the most “uhm, akshually” freaks that have the worst behavior of all: wrong all the time.

What surprises me most is that this even has any upvotes or comments. Astroturfing is my only guess.

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