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Notes from the SF peptide scene

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Re: Notes from the SF peptide scene

#91

Post by kelnos »

pphysch wrote: post #37
adregan wrote: post #19

I’m not really understanding the notion that these people are so sincere. Perhaps we have different definitions of sincerity. To my eye, the entire fascination of unsafely injecting peptides in a desire to change your being is largely the opposite of sincerity.

Yeah, isn't the entire point of SF startup culture (for the last decade++) to build personal wealth through a successful exit rather than build a sustainable business that benefits society? It's a big speculative con game... Opposite of sincere. Of course we can warp the semantics and argue that these people are "sincere" in their desire to defraud retail investors or something, but that doesn't seem to be the author…

I think this is a form of selection bias. We hear about -- and rage about -- the people you describe here because it's news, and it's outrageous.

But there are lots of people with a sincere mission who we don't hear about, because they're quietly working toward their goals.

That doesn't say that their goals are worthwhile or that what they're doing is actually good for the world, but they can still sincerely believe it is.

Most of them fail, and we hear about precious few of them. That doesn't make them any less sincere either.

Re: Notes from the SF peptide scene

#92

Post by cjbgkagh »

arjie wrote: post #87
cjbgkagh wrote: post #71

Earlier quoted context omitted.

BPC157/TB5, IPA/CJC-NoDac, VIP, and Semaglutide (ozempic). Semaglutide was the most effective long term for autoimmune but the others really helped with CCI and other physical ailments. I take a combo of modafinil in the morning and amitryptiline at night as a treatment for dysautonomia and dopamine dysregulation. I started Low Dose Naltrexone and supplemental T3 hormone and this is a good place for most with hEDS to…

If you don't mind sharing, which symptoms abated with the use of these peptides? Email in profile if you feel you'd share only in private.

The worst for me was the chronic fatigue with a strong brain fog component, pretty much all of my symptoms have abated, I still have a residual general anxiety disorder and I still get post exertional malaise so I avoid doing anything that'll take my heart rate over 150. I had pretty much all the standard hEDS symptoms though not as much MCAS and I'm very hypermobile.

Re: Notes from the SF peptide scene

#93

Post by kelnos »

halper wrote: post #5

Sometimes I have been in situations in life where I think I must be insane, because everyone else sees something I do not. I got a bit of that feeling reading this article.

It only feels that way because the author presents it in a way that makes it sound like these peptide parties are incredibly common.

But the author does throw around some numbers, with the high water mark being 34,000 people. That's still only around 4% of SF's residents. Not even remotely close to "everyone".

I've never been a part of SF's drug subcultures, so I was never likely to run into these kinds of parties in my time here. I never felt like I was somehow oblivious to everything going on around me.

Re: Notes from the SF peptide scene

#94

Post by arjie »

cjbgkagh wrote: post #92
arjie wrote: post #87

Earlier quoted context omitted.

If you don't mind sharing, which symptoms abated with the use of these peptides? Email in profile if you feel you'd share only in private.

The worst for me was the chronic fatigue with a strong brain fog component, pretty much all of my symptoms have abated, I still have a residual general anxiety disorder and I still get post exertional malaise so I avoid doing anything that'll take my heart rate over 150. I had pretty much all the standard hEDS symptoms though not as much MCAS and I'm very hypermobile.

Thank you for sharing.

Re: Notes from the SF peptide scene

#96

Post by kelnos »

oceanplexian wrote: post #64

Here comes another post reminding me of the SF crowd with Peter Pan syndrome and delusions of grandeur. Maybe if they weren’t such insufferable assholes, the rest of the country wouldn’t dig on California so much. Software is fun, but lots of people in other cities change the world without writing another AI harness. For example a group of aerospace engineers from across the country (Including Utah, Alabama, etc.) se…

Here comes another comment reminding me that people for some reason think that the experience of a small group of people somehow generalizes to some sort of dominant "culture" in a particular place.

Re: Notes from the SF peptide scene

#97

Post by kelnos »

uxp100 wrote: post #7

20% work in tech? I think that’s gone up quite a bit since I last spent a lot of time there in 2015. I would see these articles from time to time and think, people are getting the wrong idea if they haven’t been there, when I think of SF I think of middle aged Chinese people and alleycat bike races and music venues and book stores and drug dealing and gays, though tech bros are also present (and overlapping). But dam…

I mean, the author just pulled that 20% number out of his ass. Not saying it's wrong or right, but... c'mon. Let's take all of this with a big helping of salt.

Re: Notes from the SF peptide scene

#98

Post by trashface »

mh2266 wrote: post #50

WTF is any of this, is there some ELI5/OOTL explanation? I work in big tech and have never heard anyone talk about "peptides". Is this a startup scene thing or just an SF thing? (I live in New York) all of my coworkers are pretty normal, sure there are the stereotypical fitness types that are marathon training, cycling, or have a climbing gym membership but no one is talking about buying weird Chinese drugs

Derek Lowe had a good blog post about it, mostly about the problems: https://www.science.org/content/blog-post/ah-peptides-where-...

Re: Notes from the SF peptide scene

#99

Post by almost_usual »

Havoc wrote: post #57

Kinda wild to me that people are down with injecting mystery substances received from the other end of the world entirely outside any real medical chain or certainty of contents or recourse. Like black market steroids except with less track record

Some people always want the ‘hack’ or easy way out. It’s unsurprising to me.

Re: Notes from the SF peptide scene

#100

Post by NDlurker »

Aurornis wrote: post #32
lanyard-textile wrote: post #27

Earlier quoted context omitted.

I'm inclined to agree. But... I'm also inclined to believe we are not the cool people being invited to these circles :) Looking at what has happened with wegovy etc, it doesn't seem impossible.

Maybe this hits different for me because I have been to a lot of parties just like this, without getting sucked into the culture. Thats why I wrote that if you go back several years you’d find similar small social scenes around different trends: Steroids, Modafinil (when it was new and rare), RCs like 2-FA and MXE, or psychedelics depending on the era. Each time the social scenes that emerge around these have the sam…

2010 was a magical time
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