As tourists to sketchy places in Asia discovered, methanol poisoning is a real risk, even from large scale distillation. It is the quality control that matters. Illegal stills make quality control impossible, so legalisation and government certified testing can make it safe. However, this ruling is not about alcohol, it is about dissolving Federal authority exercised via the trade and commerce clause of the Constitut…
Methanol/CH3OH/MeOH is poisonous and its consumption causes a life-threatening health crisis that often results in death or permanent blindness. As little as 100 ml of methanol can kill or cause lifelong damage to one's health. One shouldn't have to restate these well-known facts but they have to be repeated at every opportunity because in many ways methanol too closely resembles ethanol/EtOH, it tastes the same and…
In real homebrew, you are not at risk of methanol poisoning. If you brew some beer (step 1 to making yourself whiskey), the alcohol makeup ends up being in a 1:1000 ratio of methanol to ethanol. Distilling does not create any more methanol, it merely concentrates it. Let's play out the worst possible scenario here, where you're targeting azeotropic ethanol, and specifically targeting methanol with your cuts. In order to end up with a 100ml of methanol, you would need to be running a batch of targeting 100L (26 gallons) of ethanol, which means starting with 2,000L (530 gallons) of beer. That is wildly outside the range of casual home distilling.
And keep in mind in order to hit that worst case scenario, the distiller needs to know enough to be making cuts, but not know to discard the first cut, which is done normally even without methanol concerns simply because it contains a bunch of really disgusting aromatics.