Earlier quoted context omitted.
I run both (LS on Mac, at least), they do different things - pi.hole is a great ad blocker which applies to all of the devices on your network. Little Snitch is doing something different - it tells you every call that every app you use is making, and allows you to approve or deny each one. So, you can block telemetry for apps, or you can block certain apps from contacting certain servers, or you can just use it to wa…
To clarify, I'm aware that pihole is not intended to run on a client OS, and doesn't monitor at a process level. I'm focused on the intended effect rather than the process itself (blocking malicious/ad servers). And I think I framed my initial question incorrectly as if LS and PiHole as subtitutes. It's perfectly fine and even preferrable to use both as layered protection. I'm just thinking however when it comes for…
Some telemetry might not be recognized by pi-hole as it is new or has nothing to do with ads.