51–60 of 161 posts
If you screen more people for the disease, and do it better, such that you reduce the incidences and fatalities in the 50+ cohort, that improvement logically implies that you must be catching incidences in the under 50 cohort. So it's going to skew the numbers. Incidences that would have been tallied in the 50+ cohort, are now counted in the under 50. E.g. a 45-year-old with a latent colorectal cancer who would previ…
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It's not simply endurance athletes though. It was 2x ultra-marathons >26 miles, or at least 5 marathons completed.
Which is way more than what original hunters and gatherers ever clock. They do move a lot, but not so much, and they alternate their activities a lot too (running, walking, resting, taking entire days off and just guarding their village). We're not really optimized for this sort of extreme endurance and long-term development of serious pathologies is unsuprising.
Earlier quoted context omitted.
Which is way more than what original hunters and gatherers ever clock. They do move a lot, but not so much, and they alternate their activities a lot too (running, walking, resting, taking entire days off and just guarding their village). We're not really optimized for this sort of extreme endurance and long-term development of serious pathologies is unsuprising.
You shouldn't so offhandedly assume a hunter-gatherer lifestyle couldn't lead to issues like increased risk of CRC, or that activities which lead to increased risk of CRC couldn't be what hunter-gatherers did. Evolution is neither fast nor perfectly precise. Plenty of animal populations have common health problems that simply weren't harmful enough to reproduction to be selected out, much less something rare and late…
This pattern is quite old. Already ancient Egyptians suffered from civilizational diseases much more than hunter-gatherers, especially the richer ones (heart attacks, gout, cancer).
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> Millennials are heavy drinkers. That's news to millenials and the graveyard of craft breweries. I thought alcohol consumption is trending off for younger generations.
Millennials are not the younger generation anymore. That refers to Gen Z and alpha.
The graph showing risk factors in age groups 18-49 is interesting - obesity, "sugary drinks (>2/day)", and sedentary lifestyle (>2 hr TV/day) are each about 1.5-2x increase in risk factor. Obesity has roughly doubled over this time period, and people are more sedentary. What I could find about "sugary drinks" seems to indicate it hasn't changed much or even dropped slightly over this time. So obesity/sedentary lifest…
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You'd be surprised. COVID-19 fundamentally altered a lot of people's habits. https://www.businessofapps.com/data/strava-statistics/
I had to have a good read of the article and put the content in ChatGPT for further more detailed analysis. I still can’t infer a single thing about how I should be surprised or how people’s habits changed, so feel free to enlighten me!
The rate of increase in childhood obesity went up during covid.
If you screen more people for the disease, and do it better, such that you reduce the incidences and fatalities in the 50+ cohort, that improvement logically implies that you must be catching incidences in the under 50 cohort. So it's going to skew the numbers. Incidences that would have been tallied in the 50+ cohort, are now counted in the under 50. E.g. a 45-year-old with a latent colorectal cancer who would previ…
This mostly can't explain the fact that mortality is also rising in under 50s. It is true mortality is rising less than incident, and that a small proportion instances of mortality could be deaths related to reasonable risks taken on from treatment side effects (to make up numbers, it makes sense to take a 5% chance of dying from treatment this year over a 80% chance of dying from cancer in 5 years), but this is prob…
Earlier quoted context omitted.
You shouldn't so offhandedly assume a hunter-gatherer lifestyle couldn't lead to issues like increased risk of CRC, or that activities which lead to increased risk of CRC couldn't be what hunter-gatherers did. Evolution is neither fast nor perfectly precise. Plenty of animal populations have common health problems that simply weren't harmful enough to reproduction to be selected out, much less something rare and late…
I don't assume anything. From what we know about health of the last surviving hunter-gatherers, they suffer significantly less from "diseases of civilization" when taken in proportion to their settled neighbours. Some of those diseases (such as high blood pressure or diabetes 2nd type) seem to be totally absent in them. Cancers do happen, but not as often. This pattern is quite old. Already ancient Egyptians suffered…
Colorectal cancer is not the same thing as high blood pressure, or type 2 diabetes, or any other cancer that isn't colorectal cancer. Diseases are not a monolith and you cannot assume low risk of some diseases means low risk of others. That is wild guesswork passed off as logic, like measuring the shadow your testicles cast on the wall and announcing it is 24.1 degrees Celsius. Ultra-marathon runners also have low risk of type 2 diabetes!
Do you have specific evidence that modern hunter-gatherers have low rates of colorectal cancer that cannot be explained by survivorship bias, screening, genetic differences, and all other confounders, and that they are representative of historical hunter-gatherers? No? Then you cannot confidently conclude that hunter-gatherers didn't experience elevated rates of CRC.
I’m in my early 30s and am starting to think about getting a screening. Problem is, it’s not trivial to do. You have to really upsell your doctor to get one so early, even though it’s a relatively benign procedure. There is a noninvasive testing method called Shield but it is way too flawed to be reliable (with poor positive rates for malignant tumors)
If you tell your doctor that a parent had polyps removed (say, recently), that will give you your best chance of getting one. Most likely, if you're in an even remotely progressive area, your doc wants you to have one, but their hands are tied by the insurance company. Afaik you dont have to provide any proof of your claim re parental polyps.
Doctors' ability to prescribe or refer is never restricted by an insurance company. If they think a patient should get whatever healthcare, they are free to say it.
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Not to be rude but, google is free: https://www.google.com/search?q=are+millenials+heavy+drinker...
Well, your first Google result is a blog post that makes my point. > For example, baby boomers are the generation with the most dramatic increase in harmful alcohol abuse. In contrast, Gen Z prefers the sober lifestyle as they are known to consume alcohol much less than any of their older counterparts, including millennials.