I've been running Windows 8 since they release the RTM version to TechNet subscribers on my primary laptop (about a month now). Short version - outside of Metro it's basically Win7SP3 and it works great. Metro is every bit the usability disaster that people have claimed when not running on a touch screen. The good news is that you really don't have to interface much with Metro at all. It replaces the start menu, but…
I like Metro (but this is coming from a mec geek - so there you go). BUT I agree it will take time to get used to. But I suspect a hack will be out shortly allowing you to by pass Metro completely. I can't imagine the corporate world being happy about Metro.