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Anti-aging injection regrows knee cartilage and prevents arthritis

scitechdaily.com

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Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#41

Post by microtherion »

mettamage wrote: post #24

Does anyone have any idea if you have arthritis what you can do to manage the symptoms? I figure there are some people here that researched it relatively well.

I've had arthrosis in both knees for several years (due to a combination of youthful sports injuries and overweight). A few years ago I saw a knee specialist who predicted I was due for knee replacement sometime soon.

On the advice of a massage therapist I instead started a habit of using a home cycling machine for half an hour each morning. So far, it has worked wonders for me, and I hope I can hold on for a decade more, by which time the injection mentioned in the article might be ready for humans.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#43

Post by asterix99 »

aeonik wrote: post #39
rixed wrote: post #21

Earlier quoted context omitted.

Evidence seems to be lacking though. Do you have any specific source in mind?

There's very good evidence coming out of UC Davis. they have MRIs, decent experimental evidence, and biochemical explanations. They have published quite a few papers over the years. You can start here, https://pmc.ncbi.nlm.nih.gov/articles/PMC9267994/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5183725/ Look up Keith Baar.

Keith Baar's videos on YT have helped me a lot; both for treating my knee pain and for increasing overall muscle strength. The videos tell you how to heal or strengthen your tendons, ligaments, and muscles.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#45

Post by lebimas »

linsomniac wrote: post #27

I have had fairly serious arthritis in my hips for close to a decade now. Cortizone shots directly into the joint have helped the worst of the flare-ups (limping on my way into the shot, having 0 pain walking out of it, lasting a year). 5+ years ago when I was looking for another injection, my PCP said "Well, time for a hip replacement." Now, for reasons I don't understand I think he was being way premature on that (…

Can you please share which stretches helped?

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#46

Post by loeg »

mettamage wrote: post #24

Does anyone have any idea if you have arthritis what you can do to manage the symptoms? I figure there are some people here that researched it relatively well.

Diclofenac (voltaren) is a topical NSAID that can be useful for managing symptoms. Over the counter in the US.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#47

Post by ldayley »

amluto wrote: post #25
JumpCrisscross wrote: post #19

Paper: https://www.science.org/doi/10.1126/science.adx6649

The supplementary material is freely available here: https://www.science.org/action/downloadSupplement?doi=10.112... It identifies the compound used as SW033291. Searching for it on clinicaltrials.gov gives no hits.

It does , however, provide the ApexBio catalog number A8709, which is this 15-PGDH inhibitor:

https://www.apexbt.com/sw033291.html

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#49

Post by marbro »

jMyles wrote: post #12
fallinghawks wrote: post #6

Earlier quoted context omitted.

The joint at the base of my thumb started telling me it's 60 years old. I stopped being able to open jars easily last year and would like to get my grip strength back.

> The joint at the base of my thumb started telling me it's 60 years old This is my biggest apprehension. I've become quite a good guitarist, and I know that can't last forever. Getting my accomplishments in while I can.

[dead]

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#50

Post by mgarfias »

linsomniac wrote: post #27

I have had fairly serious arthritis in my hips for close to a decade now. Cortizone shots directly into the joint have helped the worst of the flare-ups (limping on my way into the shot, having 0 pain walking out of it, lasting a year). 5+ years ago when I was looking for another injection, my PCP said "Well, time for a hip replacement." Now, for reasons I don't understand I think he was being way premature on that (…

I f'd my knees running track in HS - i suspect some kind of structural problem that alters the way my knees move. Sr year wsa awful, i was just about crawling to class in the morning. MRIs showed nothing and I learned to live with it and eventually it got better when I stopped running.

10ish years later I had started riding my bike a lot during the dotcom explosion induced downtime, I kept it up after I was employed again. Knee pain came back. Went to the ortho again, this time was told "oh you have a torn meniscus, lets go fix it.

So I went under and woke up to be told that my meniscus was fine, and that I had worn grooves through the cartilage and into the bone - doc told me to never run, jump, ski, ride, etc. I was to sit on the couch.

Somehow I ended up taking karate, and the knees hurt for a bit, but the stretching we did helped loosen up my hams and quads. It didnt make the knee pain go away, but it made it tolerable in that it no longer affected my day to day.

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