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HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

eurosurveillance.org

111–120 of 383 posts

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#112
post #40

I would like to add: - HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain. - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects…

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Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#113
post #40

I would like to add: - HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain. - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects…

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Who is feeding you this? Vaccines are some of the most unambiguously positive things ever developed, they're an easy win.

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#114
post #100

Earlier quoted context omitted.

Apparently HPV is responsible for some ~70% of throat cancers and ~30% of penile cancers in men. Seems pretty significant to me. If nobody knows a guy who knows a guy who had penile cancer, that's probably because people are very bad about talking about genital health. I'm sure some of the men in my life have issues with erectile dysfunction, enlarged prostates, hemmorrhoids, etc. But no one is talking about those is…

And how many men get throat and penile cancers vs other cancers and health issues? There's a reason old men crack jokes about prostate health, erectile dysfunction and incontinence rather than their dicks falling off and are way more worried about colon cancer than rectal cancer. I didn't say it wasn't a significant source of cancer. I said that nobody knows a guy who knows a guy who's dick fell off or some other ext…

> "you people"

JFC. I'm checking out of this conversation.

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#115
post #40

I would like to add: - HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain. - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects…

> - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. However, the vaccination is expensive (~1k) and it is difficult to find doctors who will do non-recommended vaccinations for self-payers. YCMV

Are there insurance plans that won't cover it? I know that a lot of plans love not paying for things but vaccines seem to be the one thing that they all at least seem fairly good at (at least in my experience).

I am currently getting the HPV series and I only had to pay my copay for the first appointment have nothing for the second one (I am assuming it will be the same for the third)

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#116
post #36

Earlier quoted context omitted.

I fail to see how e-boks makes this work. Younger people check their e-boks less frequently than average, so sending a physical letter to their address would work just as well if not better. What makes it work is the public registers.

e-boks sends a text message to the phone, so I see it much faster than a paper mail. e-boks is like gmail (and others) in that it keeps your old mail. So you can easily find old stuff, a great improvement on paper mail. I don't even check my physical mailbox once a week. Denmark is one of the very most digital countries. Physical mail is very much on the way out. We no longer has mailboxes to send mail, you have to g…

Thats all besides the point. Which was that e-boks is not making vaccine programs possible or successful.

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#117
post #98

Earlier quoted context omitted.

Is there any issue for adult males vaccinating ? I seem to remember some mention of risk by my doctor when I asked about it, but I might be misremembering.

No vaccine is without risk, but the vaccine approach is based on that risk being so low (but not zero) in comparison to the risk of not vaccinating that it is vastly the better choice.

Ok that was a bad question, let me rephrase: isn't there something particularly bad about this one for males that are already adults that makes it not recommended by doctors by default?

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#118
post #27

Everyone already knows! HPV vaccination leads to massive reduction in nasopharyngeal, penile and rectal cancer in men. The focus of messaging around HPV vaccination on ovarian cancer, female fertility and the age limitations for recommendations / free vaccination in some places are nothing short of a massive public health failure and almost scandal. Just truthfully tell the boys their dicks might fall off and see how…

> Just truthfully tell the boys their dicks might fall off and see how all of them quicklky flock to the vaccine. Every male above the age of 26 is locked out of the vaccine unless you pay out of pocket, which will be €300-€500 (or even higher). It's led to this really weird situation, where HPV vaccination for men is now recommended up to 40s but only covered up to 26yr old, and that recommendation upgrade happened…

This seems to be changing in some areas. I am in the US, in my 30's, Male and I only had my $30 copay for the first visit (nothing for my second shot)

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#119
post #100

Earlier quoted context omitted.

You could probably have gotten away with it a decade ago but that is a very poor plan in the far more critical of public health world of today. Statistically nobody even knows a guy who knows a guy who's dick fell off. Serious HPV problems for men are not even common enough to be viable urban legend. You have less to back up your DARE messaging than DARE did. It's just not gonna work. The nanosecond someone who took…

Apparently HPV is responsible for some ~70% of throat cancers and ~30% of penile cancers in men. Seems pretty significant to me. If nobody knows a guy who knows a guy who had penile cancer, that's probably because people are very bad about talking about genital health. I'm sure some of the men in my life have issues with erectile dysfunction, enlarged prostates, hemmorrhoids, etc. But no one is talking about those is…

70% of throat cancers? In a world with cigarettes and chewing tobacco? I find that a very surprising number - so surprising it's almost unbelievable.

Got a source?

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#120
post #97
post #92

Earlier quoted context omitted.

But this misunderstands how HPV works. First, there are many strains. Typical tests for oncogenic variants measure around 30 types. The vaccine I received (Gardasil-9, which I took as a male at age 35) protects against nine specific strains. Second, the body normally clears HPV naturally after 1-2 years. However, natural infection often does not provide immunity, so reinfection can easily occur (even from the same pa…

Does the vaccine guarantee immunity, by contrast?

Parent is overstating the case. Neither infection nor vaccination provides sterilizing immunity [1], but the general reasons to prefer vaccination are (in order of descending quality of evidence & reasoning):

1) you probably haven't had all N strains yet.

2a) you likely haven't been infected with the ones that cause cancer, because they're relatively rare.

2b) ...that is especially true if you're young and not sexually active.

2) being infected with one strain does not provide sterilizing cross-immunity against the other strains.

3) even if you've been infected with a strain, some of the vaccines have been shown to prevent reinfection and reactivation better than natural infection alone.

4) in general, the vaccination-mediated immunity might last longer or be "stronger" than the natural version, since the vaccines are pretty immunogenic, and the viruses are not.

But for point 4, it's well-known that vaccine efficacy is lower for people who have already seroconverted (cf [1]), so there's clearly some amount of practical immunity provided by infection.

[1] The vaccines are roughly 90% effective for the major cancer-causing strains, but it's not a simple answer, and varies a lot by how you frame the question. See table 2 here: https://pmc.ncbi.nlm.nih.gov/articles/PMC8706722/

Also be sure to see table 4 if you're a man. The data for biological men and women are surprisingly different!

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