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HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

eurosurveillance.org

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Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#91

Post by closewith »

disgruntledphd2 wrote: post #81
closewith wrote: post #48

Earlier quoted context omitted.

Okay, well Ireland has similar vaccination rates, broader childhood vaccination coverage, and no central medical records at all, so while e-boks may assist administration, it's certainly not necessary.

> no central medical records at all Which is bad, we definitely should have them. Referral data appears to be managed through Healthlink, which may just be a privatised not always used medical record system.

I'm a proponent of EHRs but not necessarily of centralised medical records, which have not been shown to improve outcomes and which do impose serious privacy risks on patients.

HealthLink is a messaging system and stores no EHRs at all. eHealth is the National EHR programme aiming to roll out EHRs by 2030 nationwide.

It will be a no-opt-out centralised EHR and combined social care record.

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#92

Post by stared »

phkahler wrote: post #86
stared wrote: post #40

I would like to add: - HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain. - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects…

>> HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. This statistic seems to be used by some people to avoid the vaccine - they figure they've already had it at some point. The biggest problem with that logic is that not all strains are as dangerous and they probably have not contracted 16 or 18 specifically. The other problem is there's still a good number of people…

But this misunderstands how HPV works. First, there are many strains. Typical tests for oncogenic variants measure around 30 types. The vaccine I received (Gardasil-9, which I took as a male at age 35) protects against nine specific strains.

Second, the body normally clears HPV naturally after 1-2 years. However, natural infection often does not provide immunity, so reinfection can easily occur (even from the same partner or a different part of your own body).

People often assume that HPV is either a lifetime infection or that recovery guarantees immunity - neither is the case!

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#93

Post by hammock »

torben-friis wrote: post #88
stared wrote: post #40

I would like to add: - HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain. - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects…

Is there any issue for adult males vaccinating ? I seem to remember some mention of risk by my doctor when I asked about it, but I might be misremembering.

There is currently no vaccine that is zero risk

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#94

Post by hammock »

phkahler wrote: post #86
stared wrote: post #40

I would like to add: - HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain. - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects…

>> HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. This statistic seems to be used by some people to avoid the vaccine - they figure they've already had it at some point. The biggest problem with that logic is that not all strains are as dangerous and they probably have not contracted 16 or 18 specifically. The other problem is there's still a good number of people…

What about the people who know they have 16 or 18? Should they still get it?

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#95

Post by inglor_cz »

tokai wrote: post #49
hagbard_c wrote: post #44

Earlier quoted context omitted.

Go and look around in former high-trust societies where this trust has broken down or is breaking down - my points of reference are the Netherlands, Sweden, Germany and to a lesser extent the UK - and you'll get your citations. What you'll probably find is that in 'marginalised areas' people have trust in governmental institutions - those which provide social welfare, healthcare, schools and such - while they have li…

Sweden is not a society were trust has broken down. Neither is Germany. Maybe the Netherlands can be argued to have a breaking down of trust. Go look at actual data, and don't rely on racist internet memes to form your arguments.

In neighboring Denmark, where they do gather and publish crime stats by the country of perp's origin, it turns out that some people (like Somalis) have up to 10 times more criminal convictions than the country baseline.

https://x.com/jonatanpallesen/status/1993654135917257214/pho...

One would have to be crazy in order to extend exactly the same trust towards a random Danish Dane vs. a random Somali Dane.

Not every negative statement about non-white people is rooted in racism, and the ugly, fanatical attitude "everyone who has a negative observation about any sort of immigrants must be racist, stupid and evil" is what upended the political spectrum and brought the far right to power in many places.

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#96

Post by actionfromafar »

CalRobert wrote: post #76
albatross79 wrote: post #75

[flagged]

Celibacy isn’t great either. Also I’d really prefer my daughters not get cancer no matter their sex lives.

That last line is key. Not everyone thinks like that, unfortunately.

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#97

Post by hammock »

stared wrote: post #92
phkahler wrote: post #86

Earlier quoted context omitted.

>> HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. This statistic seems to be used by some people to avoid the vaccine - they figure they've already had it at some point. The biggest problem with that logic is that not all strains are as dangerous and they probably have not contracted 16 or 18 specifically. The other problem is there's still a good number of people…

But this misunderstands how HPV works. First, there are many strains. Typical tests for oncogenic variants measure around 30 types. The vaccine I received (Gardasil-9, which I took as a male at age 35) protects against nine specific strains. Second, the body normally clears HPV naturally after 1-2 years. However, natural infection often does not provide immunity, so reinfection can easily occur (even from the same pa…

Does the vaccine guarantee immunity, by contrast?

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#98

Post by donohoe »

torben-friis wrote: post #88
stared wrote: post #40

I would like to add: - HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain. - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects…

Is there any issue for adult males vaccinating ? I seem to remember some mention of risk by my doctor when I asked about it, but I might be misremembering.

No vaccine is without risk, but the vaccine approach is based on that risk being so low (but not zero) in comparison to the risk of not vaccinating that it is vastly the better choice.

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#99

Post by yieldcrv »

elric wrote: post #72
stared wrote: post #40

I would like to add: - HPVs are extremely common: 80% of men and 90% of women will have at least one strain in their lives. Unless you plan to remain completely celibate, you are likely to contract a strain. - Sooner is better, but vaccination can be done at any age. Guidelines often lag behind, but vaccination makes sense even if you are currently HPV-positive. While it won't clear an existing infection, it protects…

I, a male, got vaccinated with the Gardasil 9 vaccine shortly before turning 40. Convincing my doctor to prescribe it wasn't terribly difficult, I told them a few things about my sexual history and explained some of my sexual plans, and that was that. I wish more people would get vaccinated.

Best of luck, the reason it took so long for males to be approved for Gardasil use and they slowly keep pushing it up by age is two fold:

1) if you've ever been exposed to HPV already, then the vaccine is useless

2) there is no test to determine if a male has been exposed, although there is one for females

so they just push the ages up by probability, over time. As the probability of a man being with an older and therefore unvaccinated woman decreases - since with women is the most probable - the age can rise

Re: HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

#100

Post by elric »

potato3732842 wrote: post #90
Traubenfuchs wrote: post #4

Everyone already knows! HPV vaccination leads to massive reduction in nasopharyngeal, penile and rectal cancer in men. The focus of messaging around HPV vaccination on ovarian cancer, female fertility and the age limitations for recommendations / free vaccination in some places are nothing short of a massive public health failure and almost scandal. Just truthfully tell the boys their dicks might fall off and see how…

You could probably have gotten away with it a decade ago but that is a very poor plan in the far more critical of public health world of today. Statistically nobody even knows a guy who knows a guy who's dick fell off. Serious HPV problems for men are not even common enough to be viable urban legend. You have less to back up your DARE messaging than DARE did. It's just not gonna work. The nanosecond someone who took…

Apparently HPV is responsible for some ~70% of throat cancers and ~30% of penile cancers in men. Seems pretty significant to me.

If nobody knows a guy who knows a guy who had penile cancer, that's probably because people are very bad about talking about genital health. I'm sure some of the men in my life have issues with erectile dysfunction, enlarged prostates, hemmorrhoids, etc. But no one is talking about those issues.

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