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It's even more fascinating when you have first hand experience with how much unmitigated guesswork goes into selecting psychiatric meds and their dosage.
Prozac 'no better than placebo' for treating children with depression, experts
31–40 of 561 posts
Re: Prozac 'no better than placebo' for treating children with depression, experts
#32Re: Prozac 'no better than placebo' for treating children with depression, experts
#33Re: Prozac 'no better than placebo' for treating children with depression, experts
#34SSRIs literally saved my life, no question about it. Night and day difference, from daily panic attacks destroying my life, happiness, and career, to being almost completely better in 2 weeks after starting. I tried exercise and diet and meditation and you name it, for years! , before I gave medication a go. Do not care what the science says. It 100% worked for me. Please get help if you need it, tens of millions of…
I have tried prozac in my teens and zoloft in my 30s. Prozac made me dissociate pretty hard, I found myself between classes not knowing where I was coming from or going. Zoloft did nothing but give me the zaps when I came off it.
There have been some serious efforts made to reproduce the original groundbreaking results that showed how effective SSRIs were, without much success. Anecdotally, I know plenty of people who have benefited from them, so I would not say they are ineffective as a blanket statement. I do think it’s important to understand that nobody really knows how these drugs will impact any one individual, and it’s trial and error to find something that may help.
Re: Prozac 'no better than placebo' for treating children with depression, experts
#35This reads to me like over-prescription rather than lack of efficacy but I’m also not a doctor and won’t presume my kneejerk reaction is accurate.
We saw a similar whiplash with Ritalin after over-prescribing in the 90’s/2000’s. ADHD medication absolutely works, but for a lot of people it didn’t for this reason.
Re: Prozac 'no better than placebo' for treating children with depression, experts
#36Earlier quoted context omitted.
Same here, after struggling for 39 years, glp-1 + SSRI + ADHD meds have made me a normal productive human, and 2 years ago I had pretty much given up on the possibility. Having a child forced me to fix my life, and I'm incredibly happy because of it.
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This seems a little snarky. For someone with ADHD it’s not as much about “increased” productivity but rather non-zero productivity.
Re: Prozac 'no better than placebo' for treating children with depression, experts
#37Earlier quoted context omitted.
Finding everyone’s cow is expensive and time consuming: https://antidepressantcow.org/2020/02/the-story-of-the-antid... But is the only true cure to the suffering. We’d have to undergo a massive reorganization of society (and upset a few hefty profit margins) to prioritize that, so we settle for the messy symptom management we have.
That story doesn’t work for people with depression who otherwise have very good lives. I grew up in a stable household with a loving family and both parents present and supportive. I’ve never had financial hardship, either as a kid depending on my parents to provide or as an adult providing for myself and family. I did very well in school, had plenty of friends, never had enemies, never got bullied or even talked bad…
First of all, I want to write that I am glad you found something that worked so that you are able to remain here with us.
Though, I am curious about the, "otherwise have very good lives" part.
Whose definition are you using? It seems the criteria you laid out fits a "very good life" in a sociological sense -- very important, sure. You could very well have the same definition, and perhaps that is what I am trying to ask. Would you say you were satisfied in life? Despite having a good upbringing, were you (prior to medication) content or happy?
I am by no means trying to change your opinion nor invalidate your experiences. I just struggle to understand how that can be true.
As someone that has suffered with deep depressive bouts many times over, I just cannot subscribe to the idea that depression is inherently some sort of disorder of the brain. In fact, I am in the midst of another bout now. One that's lasted about 3 or so years.
To me, I have always considered emotions/states like depression and anxiety to be signals. A warning that something in one's current environment is wrong -- even if consciously not known or difficult to observe. And if anyone is curious, I have analyzed this for myself, and I believe the etiology of my issues are directly linked to my circumstances/environment.
> I don’t think there’s a metaphorical “cow” that could have helped me.
The smart-ass in me can't help but suggest that maybe medication was your cow?
Re: Prozac 'no better than placebo' for treating children with depression, experts
#38Our 11 year old daughter was seriously depressed recently. N=1, but fluoxetine was life changing (and potentially life saving) for her, at least.
Placebo can be life changing
Re: Prozac 'no better than placebo' for treating children with depression, experts
#39SSRIs literally saved my life, no question about it. Night and day difference, from daily panic attacks destroying my life, happiness, and career, to being almost completely better in 2 weeks after starting. I tried exercise and diet and meditation and you name it, for years! , before I gave medication a go. Do not care what the science says. It 100% worked for me. Please get help if you need it, tens of millions of…
You should have tried placebo first
Re: Prozac 'no better than placebo' for treating children with depression, experts
#40SSRIs literally saved my life, no question about it. Night and day difference, from daily panic attacks destroying my life, happiness, and career, to being almost completely better in 2 weeks after starting. I tried exercise and diet and meditation and you name it, for years! , before I gave medication a go. Do not care what the science says. It 100% worked for me. Please get help if you need it, tens of millions of…
Same here, after struggling for 39 years, glp-1 + SSRI + ADHD meds have made me a normal productive human, and 2 years ago I had pretty much given up on the possibility. Having a child forced me to fix my life, and I'm incredibly happy because of it.
What’s normal anyway?