This looks great, but the IDE seems to be one of the key features, so we're going to need something other than Visual Studio. EDIT: they've got syntax highlighting for some other editors, but full completion and error reporting is still needed http://blogs.msdn.com/b/interoperability/archive/2012/10/01/...
There's a pretty impressive demo here: http://www.typescriptlang.org/Playground/
It even has auto-complete if you press "Ctr-Space" while typing a word. Considering the source for all this stuff is freely available, I don't think it'll be too long before other IDEs support it.