amphetamines feel a lot like people putting NO2 on their cars, or overclocking their computers. You might just fine in the end, but the likelihood of wear & tear catching up to you increases. It should be treated just like any other medicine, don't use it unless you really have to, and expect adverse effect (known or unknown).
AFAIK some neurodivergent brains deal with amphetamines differently and the baseline levels of chemical affected by amphetamines is different.
Wear and tear might be a thing, i don't know, but the analogy of putting NO2 in their car feels a bit off.
It'd be more like finally putting premium unleaded in your car after years of "back of the lorry" pseudo-unleaded.