I understand that this post is actually about biology and DNA, but the headline asks a broader and more interesting question than what the article itself cares to address -- At the root of this question is whether life is entirely deterministic. Either position - yes it is, or no it isn't - is unfalsifiable. And in either case, one must live as if life is not deterministic, or else one's sense of agency and meaning d…
Also, maybe the goal of the computation isn't to generate a deterministic output. Maybe it's just to compress a lot of very random input, in a way that smooths out the noise. In this way life could be essentially random on purpose, because all the varieties of randomness are better at modeling the data (the observable universe) than a classical deterministic function would be.