Expected in-depth discussions about the topic, but got pseudo-science medical advice instead. I guess HN _is_ a 'social media' after all.
Paracetamol disrupts early embryogenesis by cell cycle inhibition
131–140 of 217 posts
Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#132It's probably worth mentioning that this drug is called Acetaminophen in the US, and is the active ingredient in Tylenol and other over the counter medicines.
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If I ever had to say anything about Paracetamol, it would be:
Remember: Paracetamol is hepatotoxic, very strong for your liver. Never take it if you have been drinking alcohol or have a weak/damaged liver. Paracetamol is the worst thing you can have for hungover: it might reduce your headache but will hurt a liver that it's already under pressure by the alcohol you drank last night.
In moderation, as prescribed, shouldn't be bad. I'm more of an ibuprofen guy though (although I rarely take it).
Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#133Earlier quoted context omitted.
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I had kidney stone surgery (laser lithotripsy) in Manhattan last Friday morning and literally the first thing I was given after changing into the paper gown was 2 500mg Tylenol pills and a cup of water. I don’t know if you’re a physician but the medical staff in manhattan tend to be at the top of their game, and they are cool with Tylenol.
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Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#134Earlier quoted context omitted.
Unsure if this is related, but I’ve heard that taking painkillers for delayed onset muscle soreness will reduce muscle gains.
Same goes for icebaths, they reduce inflammation, which is the whole point of working out.
The whole point of working out is to stress the organism in order to induce a physiological adaptation. Inflammation is NOT the point, but rather an unfortunate side effect.
Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#135I never took Tylenol/Paracetamol/acetaminophen, or anything containing it or given it to my children. We never reduce fever below 39.5/103.1 either - risks of febrile seizures are overstated and if you're a responsible parent, not a lazy one, you can see if things are going South, but there are other traditional means to lower fever. People are just too spoiled nowadays! I tested positive with COVID-19 on Tuesday and…
I have not found any study published after 2020 (the year when the French minister made the statement) that advises against ibuprofen for COVID-19. But I'm not a doctor, so I'd be interested to know your source.
Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#136I never took Tylenol/Paracetamol/acetaminophen, or anything containing it or given it to my children. We never reduce fever below 39.5/103.1 either - risks of febrile seizures are overstated and if you're a responsible parent, not a lazy one, you can see if things are going South, but there are other traditional means to lower fever. People are just too spoiled nowadays! I tested positive with COVID-19 on Tuesday and…
People do that because they haven't been "educated" (even superficially) about what fever really is, which is your body working hard to fight of the infection. And messing with it is counterproductive.
They also do it with their kids because they want to help them. Also, some people have a lot on their plate, calling them lazy is not right thing to do. I have health insurance that covers me when my kids are sick (not in the US), so I can take care of them "properly ". This doesn't make me more responsible and someone else that works two jobs and can't afford to have sick kids lazy.
Also, I don't lower fever, even with my kids unless it prevents them from sleeping. But overstated is relative, it's happened to the kid next door from me. You don't want to be careless with infants.
Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#137I won't take acetaminophen (usually) learning of the liver toxicity and low overdose potential. And I have a friend that destroyed his kidneys with ibuprofen and is on a transplant list. But from what I understand acetaminophen also dulls emotional pain like from being fired or breaking up with a girlfriend which is interesting. I still prefer to take neither if I can avoid it and I'll hurt a little bit instead. Hurt…
> And I have a friend that destroyed his kidneys with ibuprofen
Acetaminophen is not ibuprofen. But I also don't like planes because a friend of mine died in a car crash.
Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#138I've always had an (unreasonable?) dislike of Paracetamol/Tylenol ever since I found out it was the #1 cause of acute liver failure in the US. Liver failure is scary. https://en.wikipedia.org/wiki/Paracetamol_poisoning
I'm finding all the 'liver failure' comments on this post fascinating. The dose is on the back on the packet, as is the time interval between doses and the maximum number of pills per day. To overdose you need to ignore that. Given all the mention of 'Tylenol' I'm assuming most of the commenters are American - is this a thing in the US where you just take a random number of pills and ignore the labelling or treat it…
I choose to believe that all of the movies and TV shows showing Americans pouring a handful of pills out of a bottle into their hands and throwing them in their mouths (then chewing them!!!) are 100% accurate to life rather than cinematic shorthand
Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#139Earlier quoted context omitted.
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I always reach for aspirin for mild pain and people have this weird idea that its way more dangerous than paracetamol because its a blood thinner and "what if you bleed for some reason and it doesnt stop" - How is that worse than guaranteed liver damage if you take paracetamol? It almost seems like there was this big push to get people away from Aspirin to tylenol and thats why people have that idea stuck in their he…
NSAIDs (which includes more than aspirin, to be fair) cause like three orders of magnitude more injuries every year than paracetamol. The majority of incidents of liver damage from paracetamol are intentional.
Re: Paracetamol disrupts early embryogenesis by cell cycle inhibition
#140Earlier quoted context omitted.
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Excedrin is the only thing besides morphine that cures my occasional but brutal headaches.
Agreed. The one thing that invariably works for me is Excedrin. Not too surprising given it has all three of the most likely solutions in a single pill.