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New treatment eliminates bladder cancer in 82% of patients

news.keckmedicine.org

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Re: New treatment eliminates bladder cancer in 82% of patients

#2
My (non-AI) Summary:

- "TAR-200 is a miniature, pretzel-shaped drug-device duo containing a chemotherapy drug, gemcitabine, which is inserted into the bladder through a catheter. Once inside the bladder, the TAR-200 slowly and consistently releases the gemcitabine into the organ for three weeks per treatment cycle."

- Phase 2 Clinical Trial

- 85 patients with high-risk non-muscle-invasive bladder cancer

- "treated patients with TAR-200 every three weeks for six months, and then four times a year for the next two years"

- 70/85 patients—the cancer disappeared and still gone 1yr later in almost 50% patients

- FDA granted TAR-200 a New Drug Application Priority Review

- Johnson & Johnson manufactures TAR-200

Re: New treatment eliminates bladder cancer in 82% of patients

#5
post #3

> The standard treatment for this type of bladder cancer is an immunotherapy drug, Bacillus Calmette-Guérin, Can anyone explain why the vaccine for TB works to treat bladder cancer?

This "drug" is a weakened form of the bacterium, which apparently stimulates immune response. So I guess it works for both TB and bladder cancer just by getting your immune system to notice something is amiss?

Re: New treatment eliminates bladder cancer in 82% of patients

#6
post #3

> The standard treatment for this type of bladder cancer is an immunotherapy drug, Bacillus Calmette-Guérin, Can anyone explain why the vaccine for TB works to treat bladder cancer?

Turning it off and then on again works in a lot of surprising places
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