> The western 12TET scale is not actually 12TET or 12EDO, we temper the scale itself and tweak some notes [...]
I think you and I must be using words differently. To me (and to Wikipedia, and everything else I've ever read, including[1] which I just consulted to make sure I'm not crazy), 12TET is a way to specify by how much you have to multiply the frequency of the first note of the scale to get the other notes' frequencies. Wikipedia[2] has a table with the numbers for 12TET (the column "Decimal value in 12-ET"), but it's very simple: you just multiply the value of the preceding note by 2^(1/12). If you take 12TET and adjust/change the notes a bit, then it's not 12TET anymore.
> EDO on fretted instruments goes back to at least the 16th century
I'd love to see a reference for that. I just consulted [1], it has a chapter called "Non-Keyboard Tuning" and it doesn't mention that (although admittedly it spends most of its time talking about violin, with a ton of references to stuff that Mozart said). The book does say that equal temperament was known for centuries before it was used, but the people who first discovered it simply didn't think it sounded good.
[1] "How Equal Temperament Ruined Harmony (and Why You Should Care)" by Ross W. Duffin
[2] https://en.wikipedia.org/wiki/12_equal_temperament