The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
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Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#2[deleted]
Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#3>The Lumina Probiotic aka BCS3-L1 is a genetically modified strain of Streptococcus Mutans that was originally billed as producing ethanol and acetoin instead of lactic acid, outcompeting the wild type upon inoculation and thus dramatically reducing incidence of caries caused by acid buildup on the teeth.
i'm yet to see an alcoholic whose regular "mouth washing" by ethanol leads to good teeth (despite ethanol being very powerful antiseptic) .
Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#4If you want to learn more about this Lumina probiotic stuff, read this article: https://www.mcgill.ca/oss/article/medical-critical-thinking-...
Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#5>The Lumina Probiotic aka BCS3-L1 is a genetically modified strain of Streptococcus Mutans that was originally billed as producing ethanol and acetoin instead of lactic acid, outcompeting the wild type upon inoculation and thus dramatically reducing incidence of caries caused by acid buildup on the teeth. i'm yet to see an alcoholic whose regular "mouth washing" by ethanol leads to good teeth (despite ethanol being v…
According to the article as I understand it, the bacteria in question directly produces formate, the suspected culprit behind the vision loss. Ethanol being produced by the bacteria is not the relevant information here
Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#6Wait, you're telling me I can get clean teeth AND free booze
Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#7n=1 isn't necessarily data, and I have other questions (the formate concentration of the probiotic variant is 4x over JH1140, but JH1140 is itself a mutant; what's the formate production of an average wildtype strain?). Methanol can cause blindness in as little as 4mL, so the amounts we're talking about are relatively small; 4mL of methanol ≅ 99mmol.
Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#8>The Lumina Probiotic aka BCS3-L1 is a genetically modified strain of Streptococcus Mutans that was originally billed as producing ethanol and acetoin instead of lactic acid, outcompeting the wild type upon inoculation and thus dramatically reducing incidence of caries caused by acid buildup on the teeth. i'm yet to see an alcoholic whose regular "mouth washing" by ethanol leads to good teeth (despite ethanol being v…
According to the article as I understand it, the bacteria in question directly produces formate, the suspected culprit behind the vision loss. Ethanol being produced by the bacteria is not the relevant information here
my point is about selling proposition of that probiotic - production of ethanol which i'd not expect to be long term healthy on its own merits, even without formate.
Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#9I doubt an oral colony could produce enough formate to be an issue.
Methanol toxicity hits in the range of grams of methanol over a short period.
I have no idea how the bacteria are applied (oral rinse) but maybe enough got ingested to colonize the intestines? That could produce enough formate.
Re: The Lumina Probiotic May Cause Blindness in the Same Way as Methanol
#10Earlier quoted context omitted.
According to the article as I understand it, the bacteria in question directly produces formate, the suspected culprit behind the vision loss. Ethanol being produced by the bacteria is not the relevant information here
my point is about selling proposition of that probiotic - production of ethanol which i'd not expect to be long term healthy on its own merits, even without formate.
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