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Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

propublica.org

1–10 of 82 posts

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#2
I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off.

I really hope another class action lawsuit is brought against Sun.

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#3
post #2

I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off. I really hope another class action lawsuit is brought against Sun.

Isn't the new direction of capitalism in America Freedom from Regulation?

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#4
post #2

I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off. I really hope another class action lawsuit is brought against Sun.

[deleted]

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#5
post #2

I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off. I really hope another class action lawsuit is brought against Sun.

How did you find out what factory the Vyvanse was made at?

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#6
post #2

I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off. I really hope another class action lawsuit is brought against Sun.

Oh boy. I've had quite the experience with my own ADHD medication (dextroamphetamine in my case, which is essentially the stuff Vyvanse metabolizes into), and when they substituted for a different brand, that brand was completely different and so totally not compatible with this body. So now I have a Brand Medically Necessary because when they tried to switch it on me I went into hypertensive crisis :)

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#7
post #2

I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off. I really hope another class action lawsuit is brought against Sun.

I have nothing but respect for physicians but my experience is that each acts as a more narrow filter than the last and, beyond their direct expertise they have very little expertise in billing, pharmacy or anything outside of their direct domain, nor do they have the bandwidth for it. Add to that the advertising phenomenon of 'ask your doctor about X' and I suspect that anything beyond the immediate care you're receiving has very little chance of receiving thought/cogent answers.

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#8
post #2

I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off. I really hope another class action lawsuit is brought against Sun.

How did you find out what factory the Vyvanse was made at?

You can figure out the generic manufacturer by matching the active ingredient with the pill shape, color, and imprints on a pill identification website. Finding the exact factory of that manufacturer is much harder though.

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#9
post #2

I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off. I really hope another class action lawsuit is brought against Sun.

Isn't the new direction of capitalism in America Freedom from Regulation?

Yes. This is a clear example of why that's bad and why these agencies need funding and competent staffing.

Re: Threat in Your Medicine Cabinet: The FDA's Gamble on America's Drugs

#10
post #2

I'm so angry right now. I did a deep dive into this at one point after being prescribed some generic Vyvanse through Sun via Dillons/Kroger. The pills smell like fish and seem like they didn't work at all. I checked some records from the FDA and Sun wasn't listed. I brought it up to my doctor and they just brushed it off. I really hope another class action lawsuit is brought against Sun.

The "fishy odor" is a classic hallmark of amine-containing compounds [1], of which Vyvanse has three [2], including a terminal amine, which is so infamous (at least in the di-amine form) for being smelly that they have delightful names like "Cadaverine" [3].

I don't know if the completely purified drug officially has an odor, but usually you get some free amines that come along for the ride. More likely, some got outside of the gelatin capsule during shipping.

[1] https://www.science.org/content/blog-post/amines-and-landsca...

[2] https://en.wikipedia.org/wiki/Lisdexamfetamine#/media/File:L...

[3] https://en.wikipedia.org/wiki/Cadaverine

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