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Social anxiety disorder-associated gut microbiota increases social fear

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Re: Social anxiety disorder-associated gut microbiota increases social fear

#6
post #4

This is gonna go viral as: just eat more yogurt to stop being awkward or whatever.

Yoghurts probably won't help, but Fecal Microbiota Transplantation might.

A team at the University of Calgary is currently recruiting participants with Major Depressive Disorder and Obsessive-Compulsive Disorder:

https://research.ucalgary.ca/participate/clinical-trial-eval...

https://research.ucalgary.ca/participate/focused-study-fmt-o...

Re: Social anxiety disorder-associated gut microbiota increases social fear

#7
They caused SAD in mice by introducing specific microbiota.

But does the system have hysteresis? Can the flip be switched the other way? Introduce antibiotics to wipe out all the microbiota and does the SAD improve?

There can be human trials for this given that antibiotics are approved low risk medicines. Clinical trials with antibiotics to clean out and reset the microbiome along with strict diets in attempt to prevent reintroduction of said microbiota.

It can even be DIY.

Re: Social anxiety disorder-associated gut microbiota increases social fear

#9
post #4

This is gonna go viral as: just eat more yogurt to stop being awkward or whatever.

The experiment looked to be the other way around. If you introduced new microbiota from patients with SAD this caused SAD in mice.

So introducing new microbiota won’t solve the problem. The theory that needs to be tested is that we know microbiota can switch SAD on, but does removal of said microbiota turn it off? It needs to be an antibiotic cleansing. It can even be DIY. People can try this on themselves. I think the unknown factor here though is whether or not a persons diet is introducing the SAD causing microbiota.

Re: Social anxiety disorder-associated gut microbiota increases social fear

#10
post #4

This is gonna go viral as: just eat more yogurt to stop being awkward or whatever.

The experiment looked to be the other way around. If you introduced new microbiota from patients with SAD this caused SAD in mice. So introducing new microbiota won’t solve the problem. The theory that needs to be tested is that we know microbiota can switch SAD on, but does removal of said microbiota turn it off? It needs to be an antibiotic cleansing. It can even be DIY. People can try this on themselves. I think t…

Do we get gut bacteria from the people around us? Where does a newborn get their gut bacteria from?
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