The lack of deep friendships feel like a 3-fold problem.
1. You can't ever be real, if you are real, you are likely to be recorded doing something someone somewhere on the largest stage in the world (the public web) that someone will disapprove of, and someone else will raise their own profile by mining your impiety to prove their own concern and moral superiority.
2. Everyone is so mobile and connected online, they never have to break the ice and talk to those around them in the breakroom or geographical space, so all of our social skills have atrophied at best, or were never learned at worst. We know just enough civility to not get in fights, but we don't know how to easily break the ice or become acquaintances.
3. All the people that live in the cities are not close with each other, they didn't grow up together and don't go to church / rotary club / male-only spaces any longer because we are all supposed to pretend to be cool liberated yuppies in a hookup culture. Can't have real ties or any strongly held beliefs, that would make you religious (or worse, Religious on an actual religion), those people are bad. So I'm okay, you're okay, and we all smile. And inside, no real connections are ever made.
Not to mention testosterone levels dropping, schools being geared towards women, always co-ed spaces, and a breakup of younger and older generations because of cultural differences there too...not that the old people are always nice.