Can we encode all of human knowledge into the DNA of some organism? How can organisms access data stored in their DNA? Imagine being born with knowledge of every Wikipedia article, or even every website. What would that be like?
Education would no longer be necessary or valued. Experience and creativity would be what everyone garners to get a job.
Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
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Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#22Can we encode all of human knowledge into the DNA of some organism? How can organisms access data stored in their DNA? Imagine being born with knowledge of every Wikipedia article, or even every website. What would that be like?
Education would no longer be necessary or valued. Experience and creativity would be what everyone garners to get a job.
Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#23Can we encode all of human knowledge into the DNA of some organism? How can organisms access data stored in their DNA? Imagine being born with knowledge of every Wikipedia article, or even every website. What would that be like?
Education would no longer be necessary or valued. Experience and creativity would be what everyone garners to get a job.
Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#24(How nobody has reference this?)
Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#25To read the data out are they basically doing de novo assembly on the sequenced reads? How are they handling all of the errors in gene sequencing? How about assembly errors? Long repeats?
Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#26Earlier quoted context omitted.
Ribosomes seem to manage just fine. :) You just encode a big marker (making sure it's not a palindrome-paired version of itself!) as a header. If you see that, it's a correct order. If not, it's not.
This header idea is great because then you only need to keep one strand and can toss the other, potentially quadrupling the amount of data storage (I'm assuming you can keep single strands of DNA stable). [Left strand] A = 00 T = 01 C = 10 G = 11 [Right strand] T = 00 A = 01 G = 10 C = 11 Anyone know these guys at Harvard, b/c this might be a way to put, at most, 2800 terabytes in a gram? (I don't know how long the h…
I can't find a copy of the original article, but it's certainly more informative than some science journalism fluff piece.
Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#27To read the data out are they basically doing de novo assembly on the sequenced reads? How are they handling all of the errors in gene sequencing? How about assembly errors? Long repeats?
If your strand length is less than or equal to the read length of your sequencer, and you have the address blocks at the start of every sequence, you don't really need to worry about assembly. Read depth and/or a checksum of some kind will take care of errors in sequencing, and with short strands or compression of some kind, long repeats aren't much of a problem either.
Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#28Can we encode all of human knowledge into the DNA of some organism? How can organisms access data stored in their DNA? Imagine being born with knowledge of every Wikipedia article, or even every website. What would that be like?
Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#29Earlier quoted context omitted.
This header idea is great because then you only need to keep one strand and can toss the other, potentially quadrupling the amount of data storage (I'm assuming you can keep single strands of DNA stable). [Left strand] A = 00 T = 01 C = 10 G = 11 [Right strand] T = 00 A = 01 G = 10 C = 11 Anyone know these guys at Harvard, b/c this might be a way to put, at most, 2800 terabytes in a gram? (I don't know how long the h…
I suspect that George's lab used a sensible encoding scheme. They're fairly sharp. I can't find a copy of the original article, but it's certainly more informative than some science journalism fluff piece.
Re: Harvard cracks DNA storage, crams 700 terabytes of data into a single gram
#30It is incredibly stable? We better don't tell evolution.