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This is a bit off topic, but what do you think about people doing nitrous recreationally? It's always concerned me that people are inhaling close to pure nitrous oxide and holding it in. I've always wondered if this creates damaging low-oxygen conditions without the normal reflexes kicking in, and if this can cause brain/neuronal damage. I believe in medical settings it's delivered in a mixture with O2, but in recrea…
I was being treated with nitrous medically. I asked the anaesthesiologist about how it works recreationally and his answer was that yes, it was mostly just hypoxia.
If someone holds their breath long enough to cause hypoxia when inhaling nitrous oxide, they have other problems. You can easily hold your breath 1-2 minutes while sitting on a couch without experiencing hypoxia. If you're experiencing euphoria as strong as what nitrous oxide causes from hypoxia, you're basically about to die.