Adipose tissue retains an epigenetic memory of obesity after weight loss

Post by tekla » Thu, Apr 17, 2025, 3:43 PM UTC

aantix wrote: post #114

anon373839 wrote: post #28

Earlier quoted context omitted.

This is self-defeating and untrue. Many people, myself included, have kept weight off for decades. But you don’t get there by thinking of your new lifestyle as “dieting”. You need to learn to love eating healthy foods in a healthy amount, and getting exercise. Eventually you can get to a place where the old foods and habits are simply unappealing.

This is not untrue. Look at the long term numbers for successfully keeping weight off, 5, 10 years out. They’re abysmal.

Post by cookiengineer » Thu, Apr 17, 2025, 3:45 PM UTC

senko wrote: post #74

david-gpu wrote: post #68

Earlier quoted context omitted.

Tell that to all the skinny endurance weekend warriors who fuel their exercise with huge amounts of sugary drinks and gummy bears. If you are curious, read about the function of GLUT4 in the membrane of skeletal muscles. Reality is more complex than memetic one-liners.

I will as soon as I see any of them gobble up a smothered burrito or Chicago pizza on their run. Do we really want to compare ultramarathon runners with couch potatoes?

Post by tekla » Thu, Apr 17, 2025, 3:46 PM UTC

dxuh wrote: post #31

cookiengineer wrote: post #21

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It's not about the weight, it's about the exercise. Start with something easy and establish a rule that won't ever be broken. If you break a rule once, you'll lose the fight. My rule, for example, when I started to train more: - start with 10 crunches every morning and evening - increase by 2 crunches every day - no exceptions When you are at ~2 months in, you can add weight training to it to get stronger. Additional…

Have you actually lost weight like that? I think exercise is a huge trap for weight loss. Cardio exercise makes you healthy, but it will also make you hungry. Especially if you are not used to it. Overweight people are usually already overeating. They can't deal with hunger and cravings well. If you make them do cardio, they will likely eat back whatever they burned and most likely much more. And even if they don't,…

Post by stonemetal12 » Thu, Apr 17, 2025, 3:53 PM UTC

krageon wrote: post #112

guerrilla wrote: post #87

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It's insane how arrogant people can be about this. You have not accounted for all of the variables and that is blatantly obvious. The phenomenon is well known and there are multi-variable equations for it, many different models. One popular model is that NEET can decrease below the caloric deficit, meaning you still gain weight by becoming subconsciously lazier despite everything feeling equally difficult subjectivel…

But it is basic physics, which is in fact being violated. It's really very normal to require exceptional proof for this. Like literally any scientific study, not just an anecdote claiming magic.

Post by joncrane » Thu, Apr 17, 2025, 4:04 PM UTC

ben7799 wrote: post #164

Aurornis wrote: post #162

Earlier quoted context omitted.

Similar adaptions occur in muscle. The extent of new muscle fiber development (hyperplasia) is debated, so there are multiples factors influencing how muscle retains some memory of past strength ability. Once you’ve reached a level of physical strength it’s easier to return to that level in the future. This has been a topic of debate in the sports world because past anabolic steroid use could therefore carry benefits…

I can't remember exactly what I was listening to, maybe some kind of NPR podcast. But the doctor was mentioning that none of the influencers influencing young people to try T and Steroids (which is rampant right now) are ever mentioning that you are on a ticking clock to infertility as soon as you start this stuff. Some people can regain their fertility but it might take years, and some people are going to be permane…