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Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

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Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#61

Earlier quoted context omitted.

And where/how does one acquire them from?

They’re available OTC basically everywhere.

They're not OTC medicines. They are prescription-only medicines.

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#62

Earlier quoted context omitted.

> I think their Epic Health computer system that needs me to confirm my date of birth every 6 weeks can find some time to suggest the HPV vaccine if it is so damn medically necessary. You're assuming that the purpose of the EHR (Epic) is to implement public health recommendations or to establish minimum standards of care. That's a reasonable assumption for someone who doesn't work in the field, but unfortunately it's…

What are? Let me make a cynical guess: 1. Reducing costs by hiring fewer people. 2. Increasing profits by decreasing care. Did I nail it or what?

You're on the right track with money, but that's not exactly how I'd describe the goals. My impression is the primary goals are getting things coded and billed properly and thoroughly, and getting things documented in a way that minimizes legal liability.

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#63
post #46

Earlier quoted context omitted.

While this advice is good, the article is discussing HSV (herpes simplex virus), not HPV (human papilloma virus), which have quite different symptoms and epidemiology. There are, as yet, no approved HSV vaccines.

Second part of the PSA, one should keep prophylactic antiviral medication on hand incase you get exposed to someone with HSV. With 60% of the population positive for HSV, everyone should have an antiviral on hand. acyclovir, famciclovir and valaciclovir https://www.ncbi.nlm.nih.gov/books/NBK525787/

HSV-targeting antivirals like acyclovir lower the chances of transmission when taken regularly by an infected individual. They do nothing if taken by those not carrying the virus. Keeping them on hand accomplishes nothing.

From the page you link:

> If you have genital herpes, you will probably be somewhat less likely to infect your partner if you use antiviral medication for prevention. The medications used for this purpose include acyclovir, famciclovir and valaciclovir. They must be taken every day over a long period of time, though. Using them as a creme or ointment is not suitable.

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#64
post #2

PSA, everyone should be getting the HPV vaccine, regardless of age and gender. https://en.wikipedia.org/wiki/HPV_vaccine https://www.mdanderson.org/publications/focused-on-health/wh... https://www.cdc.gov/cancer/hpv/oropharyngeal-cancer.html

Annoyed at how the guidance has changed on this over the years. At first it was just a narrow slice of 20 something women. Then girl teenagers. Then men and women under 30. Then under 40. If it has an association with preventing cancers, not sure why they were so reluctant to immediately open up the patient pool.

You can only sell medication after trials. The first trials were on young women, and later trials on other groups. Nobody wanted to pay for trials on all demographics before there was evidence it worked from cheaper, more focused trial. There are also barriers to doing trials on high risk groups like the elderly without first testing on lower risk demographics.

This is one reason why so much medication not to be used by pregnant women. The trials have not been done, and trials involving pregnant women are particularly expensive and risky.

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#65

Earlier quoted context omitted.

Annoyed at how the guidance has changed on this over the years. At first it was just a narrow slice of 20 something women. Then girl teenagers. Then men and women under 30. Then under 40. If it has an association with preventing cancers, not sure why they were so reluctant to immediately open up the patient pool.

I am not sure why all the replies are indicating you are anti-science or anti-vax. It is annoying to be told something from your doctor, internalize it, have your doctor suggest flu and covid vaccine for years but never HPV, and then be told on HackerNews "you should have the HPV" and now I am supposed to tell my doctor I can do his job better than him because I read something on the internet even though most doctors…

[deleted]

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#66
post #2

PSA, everyone should be getting the HPV vaccine, regardless of age and gender. https://en.wikipedia.org/wiki/HPV_vaccine https://www.mdanderson.org/publications/focused-on-health/wh... https://www.cdc.gov/cancer/hpv/oropharyngeal-cancer.html

Is the vaccine still useful post infection?

Anecdotal evidence of curative effects even for long term symptomatic infection exists.

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#67

I'm surprised there aren't any commercialized products considering its efficacy and simple origin. I also wonder if there is any way it could be modified to protect more of the body besides just saliva.

> there aren't any commercialized product

Isn't this relatively new research?

> protect more of the body

There's only one part of my body that chews gum ;)

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#68
The antiviral valacyclovir was discussed in an article in The Economist recently. Is used to treat herpes simplex or herpes zoster (shingles). What the Economist article discussed is that the drug seems to reduce the severity and onset of dementia. The drug's patent expired long ago.

I'll be seeing my doc soon and will be requesting to begin treatment.

https://en.wikipedia.org/wiki/Valaciclovir

https://pmc.ncbi.nlm.nih.gov/articles/PMC7045215/

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#69
post #2

PSA, everyone should be getting the HPV vaccine, regardless of age and gender. https://en.wikipedia.org/wiki/HPV_vaccine https://www.mdanderson.org/publications/focused-on-health/wh... https://www.cdc.gov/cancer/hpv/oropharyngeal-cancer.html

> PSA, everyone should be getting the HPV vaccine, regardless of age and gender. This is false, please don't take medical advice from an HN post. CDC guidelines do include quite a bit of discussion of patient age. [1] 1. https://www.cdc.gov/vaccines/vpd/hpv/hcp/recommendations.htm...

CDC guidelines are nonsense here and I fail to see why they would give them. Is there a vaccine shortage?

The claim is that you're more likely to catch the virus early in your life and thus "lifetime efficacy" is reduced as you grow older. Duh, this is true of any vaccine. There are various strains of HPV and you can catch them one after the other. Having HPV at 50 is just as painful as when you're 18, if not more since your immune system is less effective.

The second part of I don't understand this advice is that they say there's no HPV test for men because the result is non-actionable. What? HIV is also nearly "non-actionable" but knowing one has it definitely reduces the chances of spreading it, does it not?

I don't get it.

I got the vaccine in my thirties against doctor's advice.

Please get the vaccine if you're sexually active with more than one person, regardless of your age.

Re: Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

#70

Earlier quoted context omitted.

They’re available OTC basically everywhere.

They're not OTC medicines. They are prescription-only medicines.

Prescriptions are easy to come by. Talk to people, their signature unlocks worlds.
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