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The Dire Wolf Is Back

newyorker.com

181–190 of 208 posts

Re: The Dire Wolf Is Back

#181

Earlier quoted context omitted.

https://www.nytimes.com/2025/04/07/science/colossal-dire-wol... This however disagreed with Wikipedia, and said there was some inbreeding. That helps make this less fake.

Do you mean "interbreeding?" If so, I'd like to see the actual source for that claim.

Yes I do mean interbreeding. The rest of the NYT article ought to cite the source. I can no longer read it so you better check yourself.

Re: The Dire Wolf Is Back

#182
post #165

Earlier quoted context omitted.

14 isn't enough for you, though it is enough to influence looks to the point that it does look different enough, but how many genes need to be changed for it to count, for you? There's some 40 million differences between humans and chimpanzees, but only about 700 that are unique to humans.

Source for those numbers? Your last sentence doesn't seem to make sense.

https://www.broadinstitute.org/news/comparison-human-and-chi...

gives the 40 million (35+5). It gives by name a bunch of genes unique to humans, though doesn't count them. 300 is just an estimate, I couldn't find a specific reference to that number, thought it's widely to believed to be in the hundreds (and not, say, the millions).

Also https://www.broadinstitute.org/news/comparison-human-and-chi...

Re: The Dire Wolf Is Back

#183
post #165

Earlier quoted context omitted.

Source for those numbers? Your last sentence doesn't seem to make sense.

https://www.broadinstitute.org/news/comparison-human-and-chi... gives the 40 million (35+5). It gives by name a bunch of genes unique to humans, though doesn't count them. 300 is just an estimate, I couldn't find a specific reference to that number, thought it's widely to believed to be in the hundreds (and not, say, the millions). Also https://www.broadinstitute.org/news/comparison-human-and-chi...

There may only be a smallish number of genes that are unique to humans or chimps, but obviously that is not the only source of differences between the two species. The first press release you linked states that,

> At the protein level, 29 percent of genes code for the same amino sequences in chimpanzees and humans.

There are about 20,000 known protein-coding genes in the human genome [1], so that alone refutes the notion that there are only about 700 differences unique to humans. Besides novel unique and changes in the protein sequences themselves, changes in gene regulation is another obvious source of differences.

See this for a more thorough, and up to date, review

https://bmcgenomics.biomedcentral.com/articles/10.1186/s1286...

[1] https://www.ensembl.org/Homo_sapiens/Info/Annotation

Re: The Dire Wolf Is Back

#185

Earlier quoted context omitted.

Do you mean "interbreeding?" If so, I'd like to see the actual source for that claim.

Yes I do mean interbreeding. The rest of the NYT article ought to cite the source. I can no longer read it so you better check yourself.

THe reason I asked is because I have just read several articles in more scientific sources linked here asserting that the latest genetic evidence suggests there was no interbreeding, because wolves and dires were so genetically distant.

Re: The Dire Wolf Is Back

#187

I never realised the Dire Wolf was a real historical animal, not just a fantasy one like the Owlbear.

The fantasy 'dire wolf' and the real 'dire wolf' have close to zero in common, except that the real dire wolf was adapted for eating megafauna and thus had the strongest bite of all canines.

And therein lies the problem, they went extinct because their prey went extinct - unless you bring back the mammoths for them to hunt, they're never going to survive in the wild; and are essentially "a wolf with a bigger appetite" to keep captive.

Re: The Dire Wolf Is Back

#188
post #120

Earlier quoted context omitted.

I got really excited that it's about Minecraft's once popular modpack

Dire is still at it. New pack for Minecraft 1.21 updated as recently as a few weeks ago! https://feed-the-beast.com/modpacks/126-ftb-presents-direwol... You can even see some history/stats for all the Direwolf packs: https://feed-the-beast.com/modpacks?search=direwolf&sort=fea...

Oooooh that's crazy - I thought it was long dead! Thanks for sharing!

Re: The Dire Wolf Is Back

#189

Here's[0] a recent editorial about Colossal, the company behind this. Basically, they make some flimsy claims about conservation and combating climate change to justify creating a poor imitation of Jurassic Park. Naturally, there's some real moral dilemmas that they gloss over in pursuit of the money a few wealthy people will pay to be able to say "I saw a Mammoth!" [0]: https://arstechnica.com/science/2025/04/editor…

Every project I've seen of theirs has been like this one: take an existing animal and tweak its genome very slightly to make it look kinda like the extinct one, then declare that they've brought back the extinct species. Never mind that it's still just a wolf with 14 very specific genes tweaked. That could be just a limitation of the current technology and one that they're working on fixing—maybe some day they plan t…

I think Colossal is betting on the fact that the general public will fall for sensationalism of this sort because of the low level of biology knowledge. This story makes me think Colossal is rather better at marketing than they are at genetics.

What they've created here are not actually dire wolves but a couple of timber wolves with about a dozen edits to 12 million gene pairs and the result is creatures that have phenotypic similarities to dire wolves but not their complete genetic signature.

Re: The Dire Wolf Is Back

#190

Earlier quoted context omitted.

Don't farmers get reimbursed for livestock lost to natural predators?

Not in the USA. There a variety of random government programs that give money in ways that do not make sense. It would be better to have zero government support and have the market naturally raise prices up a bit to cover things directly. Right now, government programs are set up to take care of a variety of special interests, most of which are silly and don't really help farmers and are very wasteful. I had four gov…

This does not surprise me at all. The world would be a much better place if the leftists downvoting this weren't allowed to vote.
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