The Internet generally has devolved towards the lowest common denominator, which is the cesspool or below. Social media and content sharing sites just concentrate and magnify it.
IMO, good content creators need to go back to self-hosting as their primary location, preferably on a decent host that won't just shut them down though if they make sure they have full control of the domain name at least and a good local/backup copy of everything, getting up and running elsewhere if that host goes tits-up is relatively easy. Then upload to youtube/others as secondary channels, so you can take advantage of the infamous algorithms for exposure, the interaction features¹, and to save bandwidth²³.
Also make sure your identity everywhere is, well, identifiable - so if youtune/InsertIdentityHere goes down someone searching for InsertIdentityHere can easily find the instances hosted on other sharing sites or your central one.
More work of course, but not massively so especially if it is (or is intended to be) a money making channel rather than purely a hobby project, and worth it long-term if take-downs happen.
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[1] I would not want to manage public comments and such on a self-hosted instance, fighting spam, hate, and other such issues can become a full-time job.
[2] Essentially using them as CDNs.
[3] You might have to give low quality versions of videos to most public requests to your main site⁴, sending users to yt/other for HD+, perhaps serving ad-free high quality videos direct to those who support you via payment (via Patreon or similar).
[4] And make sure you have appropriate throughput limits⁵ in place so “going viral” doesn't result in a massive bandwidth overage bill.
[5] This could be site-wide, though you could implement finer grained controls, perhaps if a particular item becomes temporarily “too popular” start serving a _really_ low quality version and more obvious links to TY/Vimeo/… until things die down.