I have to imagine those doctors are still there doing this, it's been their life's work.
Ask HN: A friend has brain cancer: any bio hacks that worked?
311–320 of 380 posts
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#312I can recommend Lenox Hill on Netflix if you or them have not already seen it, pretty interesting watching doctors operate on and care for GBM patients - https://www.netflix.com/title/80201728 I have to imagine those doctors are still there doing this, it's been their life's work.
I enjoyed the read even though I don't think juicing can cure cancer. They mentioned studies where cancer cells were shrinking after dripping different juices onto them. It's mostly about eating your fruits and vegetables. The dude survived cancer without going through your typical Chemo.
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#313Earlier quoted context omitted.
All cancer treatments are probabilistic. There are no cures, just interventions that increase survival rates. There are no honest sentences that begin with "every cancer".
There is no diet that will even intervene with cancer, unless the patient dies. Cancer is the patient's own cell that has mutated to a point beyond apoptosis and adapted to be able to draw nutrients from cells around it. It started from just one cell. It has already evaded dietary fluctuations and adapted. EDIT: the reason I'm a spaz about this is I feel too many people focus on diet as the focus of cancer. While it…
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#314I just now checked out my theory of switching to a keto diet - this appears to be terrible advice. There appears to be some initial idea of using keto to control cancer [1]. My working theory is that cancer is a high-replication cell, and the ketogenic diet is anti-growth, increasing the probability of it outgrowing the resources available. It appears possible to starve them of glucose [2]. In reality, it appears the…
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#315Earlier quoted context omitted.
I think that's a kind sentiment, but the counter arguments would be (1) they could very likely overdose and die, and (2) an addiction changes who you are, so it's not that "they" want it, it's the addiction that wants it. Your friend is the "they" before the addiction, and likely hates themselves after every time they fall off the wagon. To be clear we don't know the exact details, so we're speculating ; I could imag…
That sounds incredibly patronizing. For some people, just being comfortable and happy for the remainder of their brief miserable life is meaning enough.
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#316I first discovered it when searching for bladder cancer therapies[1][2]
A cursory search seems to say that HA does in fact play a role in GBM[3], and that 4MU appears to reduce GBM cell proliferation[4] though it looks at a different mechanism.
In fact, there seems to be a review of its potential for treating brain cancers specifically[5]
As far as I can tell, it's a commonly prescribed drug for bile acid related issues that rarely has any side effects or risks. It appears to be safe, and to improve outcomes across many types of cancers
[1] https://www.auajournals.org/doi/full/10.1016/j.juro.2014.02....
[2] https://pmc.ncbi.nlm.nih.gov/articles/PMC11081427/
[3] https://link.springer.com/chapter/10.1007/978-94-007-7602-9_...
[4] https://www.sciencedirect.com/science/article/pii/S235230422...
[5] https://www.researchgate.net/profile/Yasser-Mustafa-3/public...
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#317Earlier quoted context omitted.
My own view is not that self-experimentation is an appropriate, let alone likely efficacious, substitute for reconciliation to the idea of one's death. I certainly don't endorse interference in others' treatment, however well-intentioned. If you want to say: "you shouldn't treat your terminal illness like a science fair project unless you possess extreme sang froid and are precommitted to the acceptance of your death…
As a pure numbers game, I’d find it more surprising if “broscience” never found a result: - a lot of terminal patients are prone to experimenting - their overall number probably eclipses the total number of trial patients in a given year by at least one order of magnitude and I’d believe two or three - they don’t have institutional barriers to what they can try, eg, they’ll fund non-patentable treatments - a lot of t…
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#318Earlier quoted context omitted.
Every single person I know who died from cancer young went down this route, from trying weird cures to going and seeing John of God in Brazil. Zero cured or delayed the cancer. All delayed acceptance and GREATLY regretted wasting that time and wishing they had had more time in the acceptance phase not the 'this can't be real' 'I can't die' 'There has to be something' denial. This can and does hurt them, and is cruel.…
Your tone policing in this thread is offensive. Apparently you know many people that have died from cancer young, and this qualifies you to know how a terminally ill person should process that emotion. You have zero qualification. How dare you imply that you know best for someone going through this. Hopefully no one reading this is ever in that situation. But I'll defer to the individual who's facing the death count…
I said nothing about how a terminally ill person should process anything. I stated what I have found to provide the best outcome when a person close to you has a terminal disease. If OP said 'my friend asked me to research...' I would have given a different response/no response.
But when OP makes it look like this is an initiative OP took upon themselves, for themselves, because they have lost too many friends, then yeah, I'm going to highlight that might not be the best possible position to come from if OP wants the best outcome for their friend. My response about outcomes it totally valid since OP asked for help with outcomes.
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#319There may be nearby clinical trials for such therapies as well: https://clinicaltrials.gov/
Re: Ask HN: A friend has brain cancer: any bio hacks that worked?
#320Earlier quoted context omitted.
↑This. Stop. No. Don't go down the false hope path. It's cruel AF and puts off acceptance, wasting time that they can put to better use post acceptance. Maybe let your friend explore what they want to do and you just give support. Celebrate what they celebrate and cry with them when they cry. Find(or better make) them some comfy/cute hats. If you want to research the things about the hospital, the procedures they are…
Errr. So your point is I should be reassuring my friend, by telling him he’s getting fantastic healthcare. I don’t get it. My friend doesn’t need reassurance. He doesn’t need to take comfort in the fact that France has good healthcare. He’s going to die and he knows it. I am here just because I want to tell him: if you want to try something crazy, and it may not work at all, there’s this. If you prefer not to, that’s…
I get what you want and why you are here, I do. Been there done that for friends and family. I lost my mom, don't think I didn't try to find every treatment, and for me she did them all no matter the pain/loss in quality of life it inflicted on her. In the end watching Joel Olsteen gave my hippie/anti christian progressive mom comfort so guess what, anti-organized religion me sat and watched Joel friggen Olsteen with her as she accepted and processed her situation, while inside I screamed 'noooooooo, we can't accept this! NOOOOOOOOOOOOO! Mom no, I can't lose you, and our final time can't be spent watching Joel friggen Olsteen!'. And on that final day, when she was suffering in worse pain than I can Imagine, I put on a brave face and told here it was OK mom, she can go now, she can have peace now, while inside I screamed 'you can not goooo! The world will end if you go!!!! You can't leave me, ever'.
Do you really think anyone is saying 'you can go now' inside when they tell someone it's OK to go? Do you really think everyone thinks their local medical care is the absolutely best in the world when they say 'man, good thing you got Doctor X, good thing we have this facility'?