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Ozempic increases risk of debilitating eye condition: studies

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Re: Ozempic increases risk of debilitating eye condition: studies

#51

Post by jessfyi »

ooooozeeeempik wrote: post #38

[flagged]

The cases of NAION observed post-Ozempic usage in Denmark is 150 (up from 60-75) out of 424,152 patients, for a rare ailment that already affects patients specifically with diabetes. Sorry to say those taking it as a "shortcut" in your words are even less susceptible.

As someone who's been fortunate enough to be fit and able to work out their entire life, not sure how there are people like you who shun and shame those trying to gain a semblance of control over their weight in a world where it does have a real impact whether they get serious medical attention or not. Your likely skewed thoughts on vanity be damned, bigger people are treated worse across the board and GLP-1 is a genuine salve.

Re: Ozempic increases risk of debilitating eye condition: studies

#52

Post by yen223 »

shadowtree wrote: post #32

[flagged]

> In Jakob Grauslund’s study, the researchers divided the patients into two groups: those who were treated with Ozempic and those who received other treatment. In the statistical analyses, age, gender, blood sugar and a wide range of other conditions were also taken into account.

They are comparing patients with diabetes in both groups

Re: Ozempic increases risk of debilitating eye condition: studies

#53

Post by munchler »

infermore wrote: post #41
shadowtree wrote: post #32

[flagged]

someone should do a study to determine whether diabetics develop blindness more often when on ozempic perhaps this is that study

Yes, this is that study:

“Patients with type 2 diabetes who are treated with the drug Ozempic have an increased risk of developing damage to the optic nerve of the eye.”

Re: Ozempic increases risk of debilitating eye condition: studies

#54

Post by amelius »

thund wrote: post #39
shadowtree wrote: post #32

[flagged]

Different damages, one is on blood vessels, the other on optic nerve

> NAION is damage to the optic nerve of the eye caused by a sudden stop of blood flow to the optic nerve.

Sounds like it's related to blood flow also.

(Didn't read remainder of article)

Re: Ozempic increases risk of debilitating eye condition: studies

#55

Post by beardedwizard »

monero-xmr wrote: post #33
beardedwizard wrote: post #24

Earlier quoted context omitted.

Someone reading this might assume its zero sum to you - as if people on Ozempic have not already been exercising and monitoring caloric intake without the associated weight loss/health results they desire - and have only chosen it because they don't want to try something else. I'm sure you aren't trying to come across as fat shaming, but the reality is of course not zero sum. Diet and exercise doesn't magically work…

Diet alone is 100% guaranteed to cause you to lose weight. It really is as easy as counting calories. It is a scientific fact. It is physically impossible to gain, or maintain weight, if you cut caloric intake sufficiently.

This is an intellectually dishonest statement.

Re: Ozempic increases risk of debilitating eye condition: studies

#56

Post by TeaBrain »

jdietrich wrote: post #18
compiler-guy wrote: post #3

Important to note that this side effect is still very rare and that we still use drugs with similarly serious and rare side effects. The authors of the study do not recommend abandoning these drugs, rather we should understand and manage the risks.

Also important to note that these studies are observational and do not prove causation. While the authors attempted to correct for covariates, it is highly likely that the patients who received semaglutide were generally sicker than those who did not. While further study is necessary and some degree of caution may be warranted, it is still entirely plausible that semaglutide has no causal influence on NAION.

The endlessly repeated truism that "these studies don't prove causation" isn't really saying anything, as the same could be said for every long term human drug study. This line of thinking was the reasoning behind ignoring the link between cancer and tobacco products for decades, because the studies establishing that link were and are observational studies, considering that a controlled experimental study on humans establishing the same would be completely unethical.

Re: Ozempic increases risk of debilitating eye condition: studies

#58

Post by intermerda »

monero-xmr wrote: post #33
beardedwizard wrote: post #24

Earlier quoted context omitted.

Someone reading this might assume its zero sum to you - as if people on Ozempic have not already been exercising and monitoring caloric intake without the associated weight loss/health results they desire - and have only chosen it because they don't want to try something else. I'm sure you aren't trying to come across as fat shaming, but the reality is of course not zero sum. Diet and exercise doesn't magically work…

Diet alone is 100% guaranteed to cause you to lose weight. It really is as easy as counting calories. It is a scientific fact. It is physically impossible to gain, or maintain weight, if you cut caloric intake sufficiently.

Eating is 100% guaranteed to cure starvation.

Not drinking is 100% guaranteed to cure alcoholism.

Buying a house is 100% guaranteed to solve homelessness.

It's really that easy.

Re: Ozempic increases risk of debilitating eye condition: studies

#59

Post by renewedrebecca »

KittenInABox wrote: post #30
Barrin92 wrote: post #19

Earlier quoted context omitted.

Civilization is built on long term sustainable practice, shortcuts in response to the lack of such practices is how civilizations burn down. Obviously T1 diabetics need to take medication because there's not much else they can do whatever side effects that has, but the topic is obviously relevant and posted here because these drugs are currently being used/abused for weight loss. Given that sustainable, side effect f…

> Given that sustainable, side effect free ways to lose weight exist (with many additional benefits) Just because it exists doesn't mean it's statistically applicable to a population of people. I've yet to see real evidence that on a population scale, sustainable and side effect free ways to lose weight exists at a statistically significant level. If you're 100+ lbs overweight and you lose it all without any medical…

Not to mention that the human body is completely opposed to losing weight, and will do anything it can to convince you that what you really need to do is to gain it back.
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