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Biological Miracle – Wood Frog

nps.gov

11–20 of 145 posts

Re: Biological Miracle – Wood Frog

#11

There are no pictures of the frogs in this article. For pictures (of thawed and frozen frogs) you can see: https://shakerlakes.org/frozen-frogs/

They also have a wiki, but not many photos. One photo is from Quebec.

The wiki also mentions that urea is produced, in addition to glucose, and both act as cryoprotectants.

https://en.m.wikipedia.org/wiki/Wood_frog

Re: Biological Miracle – Wood Frog

#14
post #7

Curious to how long the frozen structure can "survive". I wonder if it's a good idea to freeze one such frog and thaw it centuries later (an amphibian time-traveler!)

- Artificial experiment [1]: no longer than 3 months (but see disclaimer)

- New study [2]: 7 months (with 100% survival rate)

So further study seems to be needed.

[1] https://journals.biologists.com/jeb/article/216/18/3461/1160...

[2] https://journals.biologists.com/jeb/article/217/12/2193/1211...

Re: Biological Miracle – Wood Frog

#17
Wood frogs only live 3-5 years, so they probably only go through a max of 5 of these cycles. I wonder how much cellular damage they accumulate during these cycles that they can tolerate due to short lifespans. They also have ~10,000x less neurons than a mammal.

Even if you had the biochemistry that was able to do this, how many cycles could a higher life form tolerate this, assuming it would even work? Complex life seems to sacrifice some resiliency, such as the ability to regrow limbs. Amphibians already seem to be particularly adept at regeneration.

Re: Biological Miracle – Wood Frog

#18
post #17

Wood frogs only live 3-5 years, so they probably only go through a max of 5 of these cycles. I wonder how much cellular damage they accumulate during these cycles that they can tolerate due to short lifespans. They also have ~10,000x less neurons than a mammal. Even if you had the biochemistry that was able to do this, how many cycles could a higher life form tolerate this, assuming it would even work? Complex life s…

"frogs don’t freeze once and stay frozen. Instead, they spend a week or two freezing at night and thawing during the day until the temperatures drop permanently below freezing"

https://shakerlakes.org/frozen-frogs/

Re: Biological Miracle – Wood Frog

#19
post #9

Not one photo of said frog. Look, new rule: you write an article about frogs, you include a photo.

But the article explains perfectly how they look like. White eyes, glucose filled cells, frozen solid as a rock. Bang it against a table, it's definitely frozen. Throw it back underneath those leaves.

Re: Biological Miracle – Wood Frog

#20
post #8
post #5

cant even call that hibernation. There are other knock on advantages to bieng frozen solid, it would slow down and even kill a lot of infectious microbes.It may convey a certain life extension benifit. And threre is not much behavioral adaptation needed,frog gets chilly, snuggles under a leaf,freezes solid, gets defrosted 8 months later and wakes up hungry and horny, not bad.

> it would slow down and even kill a lot of infectious microbes I wouldn't count on it killing them. The cryoprotectants in the frog's body don't discriminate; they'll protect foreign bacteria just as well as the frog's cells.

I should of elaborated, many of the issues associated with,"conventional hibernation" have to do with lethal infections aquired externaly while hibernating, damp, cold, ....mold as to the cryoprotectants ,side protecting microbes, clearly gut microbes and other internal flora ,would benifit......but ,big but, would a sneeky cryosuspension routine also include a freeze and clense cycle?, why not! and easy enough to verify,right!
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