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Mitochondria Are Alive

asimov.press

121–130 of 412 posts

Re: Mitochondria Are Alive

#121

It's such highly unlikely chance events that make me think we really are alone in the universe (we = a sentient civilizational lifeform). There's just no way the long series of extremely improbable events that led to our rise was replicated anywhere else, and it took the sheer vastness of this universe for it to have emerged even once.

universe big

Re: Mitochondria Are Alive

#122

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

The Sun. As far as I’m aware we’ve never worshipped mitochondria. And unless you want to count eating which is technically true but not philosophically so, we don’t sacrifice plants or animals to mitochondria.

[deleted]

Re: Mitochondria Are Alive

#123
post #75

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

I actually never heard the phrase until I got online and saw the meme! My biology classes did have us gene editing bacteria to chance its color. That was fun! > The only one that comes close is Athlete's Foot, which makes the victim sound cool. The best cure for athletes foot is a 30 minute soak in diluted bleach. Get a wash basin, fill it with warm water, and add enough bleach so that it tingles a little bit. Do thi…

I have the same experience - never heard of it until I saw the meme. I have a feeling it’s something local to American schoolchildren.

Re: Mitochondria Are Alive

#124

Earlier quoted context omitted.

Mitochondria seems to have been an 'accident', yes. That does not mean that other lifeforms in different planets require mitochondria or equivalent organelles. As long as they can perform the necessary chemical reactions (which could be different in a different environments) and extract enough energy, they should be good. How did mitochondria evolve in the first place? Could they have remained as independent organism…

> long as they can perform the necessary chemical reactions That mitochondria are conserved as an independent organelle across almost [1] all eukaryotes, across billions of years of history, suggests this is something the nuclear can’t easily in house. [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6343361/

There are organisms without mitochondria too though. So it’s viable.

Re: Mitochondria Are Alive

#125

It's such highly unlikely chance events that make me think we really are alone in the universe (we = a sentient civilizational lifeform). There's just no way the long series of extremely improbable events that led to our rise was replicated anywhere else, and it took the sheer vastness of this universe for it to have emerged even once.

There is ~1M bacteria in a single drop of seawater.

Now multiply that by (the ocean) and multiply the interactions by X billion years.

It seems impossible for a symbiosis like this not to have happened.

No matter how low the odds are, the counts of those potential interactions bring this outcome to a certainty.

Re: Mitochondria Are Alive

#126
post #94

Mitochondria are why I’m a Rare Earther. In Earth’s history, mitochondrial endosymbiosis occurred once. Without that you don’t have the energy budget for complex life. Moreover, there may be a narrow window where it can happen: modern microbiology has defences and selection pressures that it make inhospitable to the hobbling chimeræ the first mitochondrial cells would have been. Until mitochondria, the emergence of l…

I have a chloroplast for you on line two; can you hold?

They're sensitive about the Oxygen Holocaust [1][2]?

[1] https://en.wikipedia.org/wiki/Great_Oxidation_Event

[2] https://en.wikipedia.org/wiki/Purple_Earth_hypothesis

Re: Mitochondria Are Alive

#127

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

> the mitochondria is the powerhouse of the cell

The explanation doesn't get much better at higher levels. You have the Krebs cycle which biology people religiously memorize but it doesn't really explain much either. The actual interesting part is usually handwaved away as "magical enzyme/protein" catalysis. Understanding how the mitochondrial proteins/enzyme catalysts function would usually require a graduate degree, and maybe a background in biochemistry and biophysics.

Re: Mitochondria Are Alive

#128

Earlier quoted context omitted.

Mitochondria seems to have been an 'accident', yes. That does not mean that other lifeforms in different planets require mitochondria or equivalent organelles. As long as they can perform the necessary chemical reactions (which could be different in a different environments) and extract enough energy, they should be good. How did mitochondria evolve in the first place? Could they have remained as independent organism…

> long as they can perform the necessary chemical reactions That mitochondria are conserved as an independent organelle across almost [1] all eukaryotes, across billions of years of history, suggests this is something the nuclear can’t easily in house. [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6343361/

https://en.wikipedia.org/wiki/Monocercomonoides

>It is the first eukaryotic genus to be found to completely lack mitochondria, and all hallmark proteins responsible for mitochondrial function. The genus also lacks any other mitochondria related organelles (MROs) such as hydrogenosomes or mitosomes. Data suggests that the absence of mitochondria is not an ancestral feature, but rather due to secondary loss.

Re: Mitochondria Are Alive

#129
post #49
post #41

Any time I read a mitochondria post like this, I strongly recommend that others who find the topic interesting check out Power, Sex, and Suicide by Nick Lane. Excellent book!

+1 to Nick Lane I’ve only read The Vital Question, but I felt it was a great introduction to biochem for someone not in the field.

Absolutely loved TVQ. The insight about mitochondrial DNA inheritance being exclusively from the mother, thus motivating female fingerprinting of male nucleic DNA for gamete viability (via courtship rituals, pheromones, plumage, etc)...

Re: Mitochondria Are Alive

#130
post #75

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

I actually never heard the phrase until I got online and saw the meme! My biology classes did have us gene editing bacteria to chance its color. That was fun! > The only one that comes close is Athlete's Foot, which makes the victim sound cool. The best cure for athletes foot is a 30 minute soak in diluted bleach. Get a wash basin, fill it with warm water, and add enough bleach so that it tingles a little bit. Do thi…

Do the same but with Potassium chloride or bicarbonate. Done! And way safer
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