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Mitochondria Are Alive

asimov.press

111–120 of 412 posts

Re: Mitochondria Are Alive

#111

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

Achilles tendon?

Re: Mitochondria Are Alive

#112
> If we think of mitochondria as non-living organelles, how will we ever harness their full potential?

"Alive" is a fuzzy boundary in concept space that helps humans navigate a fractally complex world. It's not a fact about mitochondria that either hides or reveals structure. We can harness the potential of viruses, and reasonable people can disagree on whether they are alive.

Re: Mitochondria Are Alive

#114

Earlier quoted context omitted.

> long as they can perform the necessary chemical reactions That mitochondria are conserved as an independent organelle across almost [1] all eukaryotes, across billions of years of history, suggests this is something the nuclear can’t easily in house. [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC6343361/

Maybe! That could also suggest that any other strategies were just out competed by this one and lost the opportunity to develop further.

> other strategies were just out competed by this one and lost the opportunity to develop further

Absolutely. It also means--however--that any niche where alternative did exist, when exposed to mitochondrial life, they lost.

Now that I think about it, it would be pretty funny if we're this universe's cheela [1], a freakishly overclocked biosphere that runs faster not because it had to but because it happened to.

[1] https://en.wikipedia.org/wiki/Dragon%27s_Egg

Re: Mitochondria Are Alive

#115

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

The Sun.

As far as I’m aware we’ve never worshipped mitochondria. And unless you want to count eating which is technically true but not philosophically so, we don’t sacrifice plants or animals to mitochondria.

Re: Mitochondria Are Alive

#116
post #75

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

I actually never heard the phrase until I got online and saw the meme! My biology classes did have us gene editing bacteria to chance its color. That was fun! > The only one that comes close is Athlete's Foot, which makes the victim sound cool. The best cure for athletes foot is a 30 minute soak in diluted bleach. Get a wash basin, fill it with warm water, and add enough bleach so that it tingles a little bit. Do thi…

According to my doctor, this can weaken the skin too much. 30 minutes is quite a long time.

Re: Mitochondria Are Alive

#117
post #110

Earlier quoted context omitted.

I think we're in agreement then -- this article is not about "did mitochondria evolve from absorbed viable organisms as opposed to evolving directly", which is an interesting question that impacts our understanding of evolution in microbiology. The article is about whether "Microchondria Are Alive" which is a useless naval-gaze.

I dunno if I agree it's a total navel gaze. For example I could easily see a scientist asking the question, "if mitochrondira are not alive, at which point did the phagocytosis of the initial prokaryotic cell lead to the mitochondria not being alive?" "What components were lost in the cell that lead to the loss of life?" I agree these aren't particularly useful, and are ultimately definitional, but definitions matter…

This is a much more interesting question, and this is what I mean by an operational definition of life. In your first question, "alive" can have useful operational definitions -- whether it is viable outside of a cell, whether it has or had its own immune system and structure, how it survived without the organelles that other full-fledged cells seem to have but mitochondria lack, etc.

The question in the abstract is not really useful except to answer trick questions in bar trivia.

Re: Mitochondria Are Alive

#118

Mitochondria are why I’m a Rare Earther. In Earth’s history, mitochondrial endosymbiosis occurred once. Without that you don’t have the energy budget for complex life. Moreover, there may be a narrow window where it can happen: modern microbiology has defences and selection pressures that it make inhospitable to the hobbling chimeræ the first mitochondrial cells would have been. Until mitochondria, the emergence of l…

I may be wrong, but I recall reading recently it had been found the same event had occurred again, fairly recently (hundreds of thousands of years, could be millions) in some species of bacteria or something like that. Here's a thought, also; maybe once this has happened, it tends to crowd out needing to happen again.

> it had been found the same event had occurred again, fairly recently

Would love to know the source if you have it.

Re: Mitochondria Are Alive

#119
It's such highly unlikely chance events that make me think we really are alone in the universe (we = a sentient civilizational lifeform). There's just no way the long series of extremely improbable events that led to our rise was replicated anywhere else, and it took the sheer vastness of this universe for it to have emerged even once.

Re: Mitochondria Are Alive

#120

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

I don't know why but for some reason, the name Mitochondria is very easy to remember even though it sounds complex.
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