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Mitochondria Are Alive

asimov.press

71–80 of 412 posts

Re: Mitochondria Are Alive

#71
The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden.

Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

Re: Mitochondria Are Alive

#72
post #47
post #30

Earlier quoted context omitted.

I think it just attacks the wholeness of ‘self’ and starts to reveal the true complexity of nature.

We didn't evolve to understand "self", and indeed most animals do not. There was no evolutionary pressure to do so. We're having to discover it piece by piece.

We had evolutionary pressure to evolve self-preservation, and that stars with self, doesn't it?

Re: Mitochondria Are Alive

#73

I read the article waiting for an answer to the question "in what operational sense does this matter?" but it never arrived. The question posed is whether we consider mitochondria to be "alive". It's just a word, who cares. What do we do differently given this assumption?

Exactly. Seems similar to "are LLMs alive"? What practical purpose would an answer to that question serve?

That seems to be an overly reductive view on the value of knowledge.

What practical purpose does studying ancient civilizations have? Why do we send expensive telescopes into space to study faraway galaxies and try to uncover mysteries of the big bang? When can we expect the results from number theory to lower the price of gas at the pump?

Re: Mitochondria Are Alive

#74

Earlier quoted context omitted.

Organelles are alive too. All active biological systems are alive. Mitochondria have for many generations now been known to have their own DNA and replicate on their own. So I’m not sure what new distinction is being drawn?

I _think_ what they mean is it's not typically listed as a "life form" in its own right, i.e., there's no Domain under which one would classify Mitochondria - maybe just calling them bacteria would capture the article's intent? So, the modification would be that we are living in symbiosis with mitochondrial bacteria, similar to how we live in symbiosis with our gut bacteria, rather than them being classified as "orga…

That's more a flaw of classification systems though. Because even if they comprise a distinct life form does not mean they need to have a unique species. Consider lichen, which comprise two (or more!) separate "species" which becomes a meaningless distinction when they cannot survive on their own, or even if they could, not in a form recognizable in any wayas they were when they were a part of the symbiotic system

Re: Mitochondria Are Alive

#75

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

I actually never heard the phrase until I got online and saw the meme!

My biology classes did have us gene editing bacteria to chance its color. That was fun!

> The only one that comes close is Athlete's Foot, which makes the victim sound cool.

The best cure for athletes foot is a 30 minute soak in diluted bleach. Get a wash basin, fill it with warm water, and add enough bleach so that it tingles a little bit.

Do this every other day 3 times, e.g. Monday, Wednesday, Friday. Problem solved.

Make sure to clean out the shoes as well, ideally not wearing any infected shoes for a few days at least, and soak the insides with Lysol a few times to prevent reinfection.

Re: Mitochondria Are Alive

#76

I read the article waiting for an answer to the question "in what operational sense does this matter?" but it never arrived. The question posed is whether we consider mitochondria to be "alive". It's just a word, who cares. What do we do differently given this assumption?

It doesn't seem the article addresses this, but I'd ask these questions: "would it be possible that mitochondria's evolutional interest and the organism's interest are not aligned?" "how many independent DNA can an organism possess?" "why mitochondria do not elicit immune reactions? Or can they?"

Re: Mitochondria Are Alive

#77

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

Excellent point.

Are there mitochondria in neurons?

Re: Mitochondria Are Alive

#78
Mitochondria are why I’m a Rare Earther.

In Earth’s history, mitochondrial endosymbiosis occurred once. Without that you don’t have the energy budget for complex life. Moreover, there may be a narrow window where it can happen: modern microbiology has defences and selection pressures that it make inhospitable to the hobbling chimeræ the first mitochondrial cells would have been.

Until mitochondria, the emergence of life from nothing is plausible. With mitochondria, its progression to complex, multicellular and intelligent life makes sense. Both processes in small steps can be replicated, more or less, in the lab. But that one moment is not and has not been. As a result, I think the universe has lots of living slop but very few plants and animals.

(Aside, look at ATP go: https://www.youtube.com/watch?v=lUrEewYLIQg&t=939s)

Re: Mitochondria Are Alive

#79

The fact that every child on the planet is religiously taught that the mitochondria is the powerhouse of the cell is all the evidence I need that we're upholding a primordial contractual agreement and these are the conditions to which we are beholden. Name a single biological entity that has a better PR department. The only one that comes close is Athlete's Foot, which makes the victim sound cool.

Excellent point. Are there mitochondria in neurons?

> Are there mitochondria in neurons?

Yes [1].

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC7373250/

Re: Mitochondria Are Alive

#80

Earlier quoted context omitted.

"If we think of mitochondria as non-living organelles..." mitochondria were thought to just be a component of the cell. But they have their own DNA separate from that in the cell's nucleus. They replicate on their own like bacteria.

> mitochondria were thought to just be a component of the cell. ... hundreds of years ago, for a short time after they were discovered. We know that they behave like bacteria for almost as long as we know that they exist.

They "behave as" bacteria. Are they bacteria? Are they 'alive' by themselves? That's the distinction.
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